Abstract
Growth arrest lines appear as dense sclerotic lines parallel to the growth plate of long bones on radiography. We describe the case of a 9-year-old female with growth arrest lines initially masquerading as lymphoma involvement on 99mTc-MDP bone scintigraphy who had been treated with chemotherapy for non-Hodgkin’s lymphoma about 3 years previously. Subsequent regional bone SPECT/CT clearly diagnosed the growth arrest lines, and retrograde review of previous bone scintigraphy demonstrated line migration in this patient. Growth arrest lines should be considered a possible diagnosis on bone scintigraphy, especially in the surveillance of children who have experienced severe childhood infections, malnutrition, immobilization, or treatment with immunosuppressive or chemotherapeutic drugs that may inhibit bone growth.
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Chanwoo Kim, Ji Young Kim, Yun Young Choi, Seunghun Lee, and Young-Ho Lee declare that they have no conflict of interest and no source of funding.
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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation and with the Helsinki Declaration of 1975, as revised in 2000. The study design and exemption of informed consent were approved by the Institutional Review Board of Hanyang University Seoul Hospital.
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Kim, C., Kim, J.Y., Choi, Y.Y. et al. Growth Arrest Line Mimicking Lymphoma Involvement: The Findings of 99mTc-MDP Bone SPECT/CT and Serial Bone Scan in a Child with Non-Hodgkin’s Lymphoma. Nucl Med Mol Imaging 50, 157–160 (2016). https://doi.org/10.1007/s13139-016-0398-9
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DOI: https://doi.org/10.1007/s13139-016-0398-9