Abstract
Tenofovir, used in the treatment of chronic hepatitis B and HIV, is known for its side effects on the kidneys and bones. We share interesting images of a patient with tenofovir-induced osteomalacia on Technetium-99 m hydroxymethyelene (Tc-99 m HDP) bone scintigraphy. Pattern recognition of this bone scintigraphy and correlation with the clinical history is essential to avoid misdiagnosis.
Change history
19 November 2018
The original version of this article unfortunately contained a mistake. The presentation of the author names was incorrect. The correct information is given here.
19 November 2018
The original version of this article unfortunately contained a mistake. The presentation of the author names was incorrect. The correct information is given here.
References
Magalhaes-Costa P, Matos L, Barreiro P, Chagas C. Fanconi syndrome and chronic renal failure in a chronic hepatitis B monoinfected patient treated with tenofovir. Rev Esp Enferm Dig. 2015;107:512–4.
Hall AM, Hendry BM, Nitsch D, Connolly JO. Tenofovir-associated kidney toxicity in HIV infected patients: a review of the evidence. Am J Kidney Dis. 2011;57:773–80.
Martinez MVG, Gallardo FG, Pirogova T, Garcia-Samaniego J. Bone scintigraphy and secondary osteomalacia due to nephrotoxicity in a chronic hepatitis B patient treated with tenofovir. Rev Esp Med Nucl Imagen Mol. 2014;33:103–5.
Acknowledgment
The authors would like to thank the Director-General of Health Malaysia for the permission to publish this paper.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
Alex Khoo Cheen Hoe and Lee Yeong Fong declare that they have no conflict of interest.
Ethical Statement
The study was approved by an institutional review board or equivalent and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. The subject in the study gave written informed consent.
Rights and permissions
About this article
Cite this article
Hoe, A.K.C., Fong, L.Y. Bone Scintigraphy and Tenofovir-Induced Osteomalacia in Chronic Hepatitis B. Nucl Med Mol Imaging 51, 195–196 (2017). https://doi.org/10.1007/s13139-016-0395-z
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13139-016-0395-z