Abstract
Aim-Background
The aim of the presentation is to show the value of the radical excision of an interesting case of the retroperitoneal liposarcoma. Retroperitoneal sarcomas are malignant tumours arising from mesenchymal cells, which are usually located in muscle, fat, and connective tissues. One-third of malignant tumours located in the retroperitoneum are sarcomas, and approximately 15% of soft tissue sarcomas arise in the retroperitoneum.Complete resection is mandatory for the cure of liposarcoma.
CasePresentation
The authors reported a 65-year old male that presented with complaints of painless progressive distension of abdomen for the last 10 years, which was associated with. significant weight loss and loss of appetite. Contrast Enhanced Computed Tomography of abdomen and CT angiography showed the features likely suggestive of liposarcoma. Patient underwent exploratory laparotomy with complete resection of the tumor. Histopathology of resected specimen revealed it to be a well differentiated liposarcoma.
Conclusion
The management of retroperitoneal sarcomas consists of complete resection of the tumour, followed by adjuvant radiotherapy, reduces local recurrence but does not affect overall survival, and, combined with surveillance for early detection of recurrence or metastases, in our case.therapeutic embolization, proved to be useful preoperatively, allowing tumour shrinkage, and reduced blood loss during resection.
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References
Jacob MS, Patel S, Sasken H, et al. Retroperitoneal liposarcoma: A case report, International Journal of Case Reports and Images 2014; 5:108–12
Goertz RS, Lenfers BH, Goertz GH. Huge liposarcoma of the left retroperitoneum. Am J Surg 2009; 197:e59-e60
Hassan I, Park SZ, Donohue JH, et al. Operative management of primary retroperitoneal sarcomas: a reappraisal of an institutional experience. Ann Surg 2004; 239:244–50
Inoue K, Higaki Y, Yoshida H. Giant retroperitoneal liposarcoma. Int J Urol 2005; 12:220–2
Mohanty R, Bhat MN, Chawla SC. Retroperitonial atypical lipomatous tumour—a case report. Indian J Pathol Microbiol 2000; 43:157–60
Gupta NP, Yadav R. Renal sparing surgery for perirenal liposarcoma: 24 months recurrence free follow up. Int Braz J Urol 2007; 33:188–91
Perez EA, Gutierrez JC, Moffat FL, et al. Retroperitoneal and truncal sarcomas: prognosis depends upon type not location. Ann Surg Oncol 2007; 14:1114–22
Hashimoto Y, Hatakeyama S, Tachiwada T, et al. Surgical treatment of a giant liposarcoma in a Japanese man. Adv Urol 2010; 2010:943073
Lewis JJ, Leung D, Woodruff JM, et al. Retroperitoneal softtissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg 1998; 228:355–65
McCallum OJ, Burke JJ, Childs AJ, et al. Retroperitoneal liposarcoma weighing over one hundred pounds with review of the literature. Gynecol Oncol 2006; 103:1152–4
Fernandez-Ruiz M, Rodriguez-Gil Y, Guerra-Vales JM, et al. Primary retroperitoneal liposarcoma: clinical and histological analysis of ten cases. Gastroenterol Hepatol 2010; 33:370–6
Antinori A, Antonacci V, Magistrelli P. Giant retroperitoneal liposarcoma. Am J Surg 2002; 184:56–7
Goertz RS, Lenfers BH, Goertz GH. Huge liposarcoma of the left retroperitoneum. Am J Surg 2009; 197:e59–e60
Hassan I, Park SZ, Donohue JH, et al. Operative management of primary retroperitoneal sarcomas: a reappraisal of an institutional experience. Ann Surg 2004; 239:244–50
Stoeckle E, Coindre JM, Bonvalot S, et al. Prognostic factors in retroperitoneal sarcoma: a multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group. Cancer 2001; 92:359–68
Herrera-Gomez A, Ortega-Gutierrez C, Betancourt AM, et al. Giant retroperitoneal liposarcoma. World J Surg Oncol 2008; 6:115
Singer S, Antonescu CR, Riedel E, et al. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Annals of Surgery 2003; 238: 358–71
Russell WO, Cohen J, Enzinger F. A clinical and pathological staging system for soft tissue sarcomas. Cancer 1977; 40:1562–70
Leão P, Vilaça S, Oliveira M, et al. Giant recurrent retroperitoneal liposacrcoma initially presenting as inguinal hernia: review of literature. Int Journal of Surgery case Report 2012; 3:103–6
Lawrence WJr, Donegan WL, Natarajan N, et al. Adult soft tissue sarcomas. A pattern of care survey of the American College of Surgeons. Ann Surg 1987; 205:349–59
Wanchick K, Lucha P. Dedifferentiated retroperitoneal liposarcoma presenting as lower gastrointestinal bleeding, a case report and review of the literature. Military Medicine 2009; 174:328–30
Mullinax JE, Zager JS, Gonzalez RJ. Current Diagnosis and Management of Retroperitoneal Sarcoma. Cancer Control 2011; 18:177–87
Pisters PW, O’Sullivan B. Retroperitoneal sarcoma: combined modality treatment approaches. Curr Opin Oncol 2002; 14:400–5
Mendenhall WM, Zlotecki RA, Hochwald SN, et al. Retroperitoneal soft tissue sarcoma. Cancer 2005; 104:669–75
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Kumar, N., Verma, U., Saurabh, A. et al. A huge retroperitoneal liposarcoma. Hellenic J Surg 88, 364–368 (2016). https://doi.org/10.1007/s13126-016-0348-0
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DOI: https://doi.org/10.1007/s13126-016-0348-0