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Normal postoperative inflammatory response in patients with gastric cancer submitted to total and partial distal gastrectomy

  • Prospective Clinical Study
  • Published:
Hellenic Journal of Surgery

Abstract

Background

The removal of the stomach causes an acute inflammatory response. In some cases, this response is exaggerated due to complications. The purpose of this study was to describe the normal inflammatory response to gastrectomy.

Methods

This is a prospective analysis of patients submitted to gastrectomy for gastric cancer. The cohort was divided into complicated and uncomplicated patients. Uncomplicated patients were subdivided into total gastrectomy and partial gastrectomy. The main outcome measure was to compare the inflammatory response of uncomplicated and complicated patients.

Results

Preoperative values were similar between groups. At 24h after gastrectomy, complicated patients showed significantly higher values for D-dimer, CRP and WBC, and lower levels of albumin. Further analysis comparing uncomplicated patients showed normal preoperative values, and expected postoperative changes.

Conclusions

The normal systemic inflammatory response to gastrectomy was mild. Elevations of inflammatory values are reliable parameters for identifying early postoperative inflammatory complications.

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Authors and Affiliations

  1. Department of Surgery, Hospital de La Serena, Department of Clinics, Universidad Católica del Norte, Antofagasta, Chile

    M. A. Beltrán & F. Arcos

  2. Department of Clinics, Universidad Católica del Norte, Department of Surgery, Hospital de Ovalle, Antofagasta, Chile

    J. Arcos & E. Astudillo

  3. P.O. Box 912, Manuel Antonio Caro 2629 IV Región, La Serena, Chile

    M. A. Beltrán

Authors
  1. M. A. Beltrán
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  2. J. Arcos
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  3. F. Arcos
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  4. E. Astudillo
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Corresponding author

Correspondence to M. A. Beltrán.

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Beltrán, M.A., Arcos, J., Arcos, F. et al. Normal postoperative inflammatory response in patients with gastric cancer submitted to total and partial distal gastrectomy. Hellenic J Surg 87, 387–393 (2015). https://doi.org/10.1007/s13126-015-0245-y

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  • DOI: https://doi.org/10.1007/s13126-015-0245-y

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