Abstract
Aim-Background
The aim is to present the results of a retrospective study comparing a) choledochoscopy in open and laparoscopic Common Bile Duct Exploration (CBDE) regarding the clearance of Common Bile Duct (CBD) from stones, b) open CBDE with and without choledochoscopy, and c) transcystic vs. transductal laparoscopic choledochoscopy.
Patients-Methods
Data were extracted from the medical records of 251 patients who had undergone open or laparoscopic Common Bile Duct Exploration. We excluded all those undergoing successful ERCP and sphincterotomy. The patients were separated into the following groups
Group A: 127 patients who underwent Open CBDE; subgroup A1 comprised 52 patients who underwent Open CBDE with flexible choledochoscopy and intraoperative cholangiography (open CBDE+FCS+IOC), and Subgroup A2 included 75 patients who underwent Open CBDE with cholangiography (open CBDE+IOC).
Group B: 124 patients who underwent Laparoscopic CBDE; subgroup B1 included 15 patients undergoing transcystic choledochoscopy, and subgroup B2 comprised 109 patients who underwent transductal choledochoscopy.
Results
The stone clearance rate in group A1 (open CBDE +FCS+IOC) was 98%, and in group A2 (open CBDE +IOC) it was 93%. However, the difference in the success rate between the choledochoscopic and “blind” technique was of no statistical significance (p=0.235). Similarly, no statistical significance was found between the success rates of open (98%) vs. laparoscopic (94%) choledochoscopy (p=0.869), or transcystic (Group B1) vs. transductal (GroupB2) laparoscopic choledochoscopy (87% vs. 95% respectively) (p=0.207), although greater success was noted in favour of transductal choledochoscopy. The conversion rate of transductal laparoscopic CBDE was 8%, and the main reason for conversion was stone impaction.
Conclusion
No statistical difference is noted in stone clearance rate between flexible choledochoscopy (FCS) and intraoperative cholangiography. However, intraoperative cholangiography has better outcomes regarding stone clearance when it is assisted by choledochoscopy. A search of the literature found no available data comparing the success rate of open vs. laparoscopic choledochoscopy. Our study demonstrated that the difference in the stone clearance rate between the two approaches was not statistically significant. Laparoscopic transcystic CBDE is less invasive and is associated with a lower complication rate, but it has higher failure rates compared to the transductal approach, although the difference is of no statistical significance.
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References
Freitas ML, Bell RL, Duffy AJ: Choledocholithiasis: Evolving standards for diagnosis and management. World J Gastroenterol 2006;12:3162–3167.
Hungness ES, Soper NJ: Management of common bile duct stones. J Gastrointest Surg 2006;10:612–619.
Lyass S, Phillips EH: Laparoscopic transcystic duct common bile duct exploration. Surg Endosc 2006;20 Suppl 2:S441–445.
Chander J, Vindal A, Lal P, Gupta N, Ramteke VK: Laparoscopic management of cbd stones: An indian experience. Surg Endosc 2011;25:172–181.
Wright BE, Freeman ML, Cumming JK, Quickel RR, Mandal AK: Current management of common bile duct stones: Is there a role for laparoscopic cholecystectomy and intraoperative endoscopic retrograde cholangiopancreatography as a single-stage procedure? Surgery 2002;132:729–735; discussion 735–727.
Topal B, Aerts R, Penninckx F: Laparoscopic common bile duct stone clearance with flexible choledochoscopy. Surg Endosc 2007;21:2317–2321.
Tokumura H, Umezawa A, Cao H, Sakamoto N, Imaoka Y, Ouchi A, Yamamoto K: Laparoscopic management of common bile duct stones: Transcystic approach and choledochotomy. J Hepatobiliary Pancreat Surg 2002;9:206–212.
Campagnacci R, Baldoni A, Baldarelli M, Rimini M, De Sanctis A, Di Emiddio M, Guerrieri M: Is laparoscopic fiberoptic choledochoscopy for common bile duct stones a fine option or a mandatory step? Surg Endosc 2010;24:547–553.
Overby DW, Apelgren KN, Richardson W, Fanelli R: Sages guidelines for the clinical application of laparoscopic biliary tract surgery. Surg Endosc 2010;24:2368–2386.
Sgourakis G, Lanitis, S, Zaphiriadou, P, Korontzi, M, Kontovounisios, Ch, Karaliotas, Ch, Karaliotas, Ch, C.: A retrospective case — control study of one stage laparoscopic vs endoscopic first management if common bile duct stones. Hellenic Journal of Surgery 2012;84:41–47.
Pierce RA, Jonnalagadda S, Spitler JA, Tessier DJ, Liaw JM, Lall SC, Melman LM, Frisella MM, Todt LM, Brunt LM, Halpin VJ, Eagon JC, Edmundowicz SA, Matthews BD: Incidence of residual choledocholithiasis detected by intraoperative cholangiography at the time of laparoscopic cholecystectomy in patients having undergone preoperative ercp. Surg Endosc 2008;22:2365–2372.
Rojas-Ortega S, Arizpe-Bravo D, Marin Lopez ER, Cesin-Sanchez R, Roman GR, Gomez C: Transcystic common bile duct exploration in the management of patients with choledocholithiasis. J Gastrointest Surg 2003;7:492–496.
Moore KB, Adrales GL, Mastrangelo MJ, Jr.: Laparoscopic common bile duct exploration. Curr Surg 2004;61:294–296.
Paganini AM, Guerrieri M, Sarnari J, De Sanctis A, D’Ambrosio G, Lezoche G, Perretta S, Lezoche E: Thirteen years’ experience with laparoscopic transcystic common bile duct exploration for stones. Effectiveness and long-term results. Surg Endosc 2007;21:34–40.
Wenner DE, Whitwam P, Rosser J, Hashmi S, Wenner DE, 3rd: A stone extraction facilitation device to achieve an improved technique for performing lcbde. Surg Endosc 2005;19:120–125.
Vecchio R, MacFayden, BV: Laparoscopic common bile duct exploration. Langenbeck’s Arch Surg 2002;387:45–54.
Petelin JB: Laparoscopic common bile duct exploration. Surg Endosc 2003;17:1705–1715.
Cushieri A, Lazoche, E, Morino, M: Eaes multicenter prospective randomised trial comparing two-stage vs single stage management of patients with gallstone disease and ductal calculi. Surg Endosc 1999;13:927–952.
Paganini AM, Guerrieri M, Sarnari J, De Sanctis A, D’Ambrosio G, Lezoche G, Lezoche E: Long-term results after laparoscopic transverse choledochotomy for common bile duct stones. Surg Endosc 2005;19:705–709.
Karaliotas C, Sgourakis G, Goumas C, Papaioannou N, Lilis C, Leandros E: Laparoscopic common bile duct exploration after failed endoscopic stone extraction. Surg Endosc 2008;22:1826–1831.
Savita KS, Bhartia VK: Laparoscopic cbd exploration. Indian J Surg 2010;72:395–399.
Zinner JM, Ashley, W.S.: Maingot’s abdominal operations. 11th edition 2007
Ludwig K, Bernhardt J, Lorenz D: Value and consequences of routine intraoperative cholangiography during cholecystectomy. Surg Laparosc Endosc Percutan Tech 2002;12:154–159.
Cai H, Sun D, Sun Y, Bai J, Zhao H, Miao Y: Primary closure following laparoscopic common bile duct exploration combined with intraoperative cholangiography and choledochoscopy. World J Surg 2012;36:164–170.
Ford JA, Soop M, Du J, Loveday BP, Rodgers M: Systematic review of intraoperative cholangiography in cholecystectomy. Br J Surg 2011;99:160–167.
Wood T, MacFadyen Jr., B.V.: Diagnostic and therapeutic choledochoscopy. Seminars in Laparoscopic Surgery 2000;7:288–294.
Riciardi R, Islam S, Canete JJ, Arcand PL, Stoker ME: Effectiveness and long-term results of laparoscopic common bile duct exploration. Surg Endosc 2003;17:19–22.
Rojas Ortega S, Arizpe Bravo D, Marin Lopez E, Cesin Sanchez R, San Roman GR: [exploration of biliary tracts for laparoscopy for treatment of choledocholithiasis]. Rev Gastroenterol Mex 2004;69 Suppl 3:112–116.
Nathanson LK, O’Rourke NA, Martin IJ, Fielding GA, Cowen AE, Roberts RK, Kendall BJ, Kerlin P, Devereux BM: Postoperative ercp versus laparoscopic choledochotomy for clearance of selected bile duct calculi: A randomized trial. Ann Surg 2005;242:188–192.
Kelly MD: Results of laparoscopic bile duct exploration via choledochotomy. ANZ J Surg 2010;80:694–698.
Jameel M, Darmas B, Baker AL: Trend towards primary closure following laparoscopic exploration of the common bile duct. Ann R Coll Surg Engl 2008;90:29–35.
Santo MA, Domene CE, Riccioppo D, Barreira L, Takeda FR, Pinotti HW: Common bile duct stones: Analysis of the videolaparoscopic surgical treatment. Arq Gastroenterol 2012;49:41–51.
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Korontzi, M.I., Karaliotas, C., Sgourakis, G. et al. Choledochoscopy as a diagnostic and therapeutic tool for common bile duct stones. Hellenic J Surg 84, 347–355 (2012). https://doi.org/10.1007/s13126-012-0051-8
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DOI: https://doi.org/10.1007/s13126-012-0051-8

