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Clinical Value of 3D-Printed Navigation Technology Combined with Neuroendoscopy for Intracerebral Hemorrhage

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Abstract

Intracerebral hemorrhage (ICH) is the most common form of hemorrhagic stroke with high morbidity and mortality. Rapid and massive bleeding may compress the brain tissue, causing space-occupying and pathological effects, such as reduced local cerebral blood flow, acidosis, and inflammatory and immune responses. Although the development of minimally invasive technique provides a new option for the treatment of ICH, their application is limited due to the difficulty in achieving accurate puncture localization under the guidance of the marks on CT. We selected 30 patients treated with neuroendoscopic surgery guided by 3D-printed navigation technology (experimental group) and 30 patients treated with neuroendoscopic surgery guided by hand-painted on the patient’s body surface according to the marks on CT (control group). Our results showed that patients in the experimental group had a lower number of intraoperative punctures, shorter operation time, less intraoperative blood loss, higher hematoma clearance rate, and smaller volume of perihematomal edema than the patients in the control group. Moreover, patients in the experimental group had higher Glasgow Coma Scale score at discharge, shorter postoperative hospitalization time and ICU stay, and a lower rate of postoperative complications, despite the lack of statistically significant differences. In addition, no statistically significant differences were observed in mortality and Glasgow Outcome Scale score between the two groups. In conclusion, 3D-printed navigation technology used for the neuroendoscopic hematoma removal is a more reliable and less invasive approach in the treatment of ICH. This technique has great application prospects and deserves promotion in the future clinical practice.

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Acknowledgements

We thank Professor Li who helped us with language editing.

Funding

This work was financially supported by the Dongguan Social Science and Technology Development (General) Project (No. 2018507150401452).

Author information

Author notes

  1. Yuqian Li, Hongyu Cheng, and Zhenzhu Li contributed equally to this study.

Authors and Affiliations

  1. Department of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, Shaanxi, China

    Yuqian Li

  2. Department of Ultrasound Diagnosis, Tangdu Hospital, Air Force Medical University, Xi’an, Shaanxi, China

    Hongyu Cheng

  3. Department of Neurosurgery, Binzhou Medical University Hospital, Binzhou, Shandong, China

    Zhenzhu Li

  4. Department of Neurosurgery, The Second Hospital Affiliated of Xi’an Medical University, Xi’an, Shaanxi, China

    Haikang Zhao

  5. Department of Neurosurgery, PLA 982 hospital, Tangshan, Hebei, China

    Jiancai Wang

  6. Department of Neurosurgery, Dalang Hospital, Dongguan, Guangdong, China

    Peng Wang & Jun Zhang

  7. Department of Intensive Care Unit, Dalang Hospital, Dongguan, Guangdong, China

    Tongxin Jin

  8. Department of Anesthesiology, Dalang Hospital, Dongguan, Guangdong, China

    Guiyong Zheng

  9. Department of Radiology, Dalang Hospital, Dongguan, Guangdong, China

    Haoxiang Ye

  10. Department of Neurosurgery, Dongguan People’s Hospital, Affiliated Dongguan People’s Hospital of Southern Medical University, Dongguan, China

    Shaopeng Li

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  1. Yuqian Li
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  6. Peng Wang
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  7. Tongxin Jin
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  8. Guiyong Zheng
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  10. Shaopeng Li
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  11. Jun Zhang
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Corresponding authors

Correspondence to Shaopeng Li or Jun Zhang.

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Ethics Approval and Consent to Participate

The present study was approved by the Ethics Committee of Tangdu Hospital, Air Force Medical University and Dalang Hospital, Dongguan City, China. All patients in the present study provided written informed consent.

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Study participants provided their consent for the publication of any data/associated images.

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The authors declare no competing interests.

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Cite this article

Li, Y., Cheng, H., Li, Z. et al. Clinical Value of 3D-Printed Navigation Technology Combined with Neuroendoscopy for Intracerebral Hemorrhage. Transl. Stroke Res. 12, 1035–1044 (2021). https://doi.org/10.1007/s12975-021-00893-6

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  • DOI: https://doi.org/10.1007/s12975-021-00893-6

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