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What Can We Learn from Randomized Clinical Trials About the Construct Validity of Self-Report Measures of Mindfulness? A Meta-Analysis

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Abstract

Because they provide data on responsiveness to experimental manipulation, clinical trials involving mindfulness-based interventions are a source of evidence for the construct validity of self-report measures of mindfulness. Within-group and between-group changes in mindfulness were examined from randomized clinical trials comparing mindfulness interventions to other bona fide treatment comparison conditions or waitlist control conditions. We also examined changes in clinical outcomes and the magnitude of these changes relative to changes in mindfulness. We included 69 published studies representing 55 unique samples (n = 4743). Self-report mindfulness measures showed relatively larger gains in mindfulness intervention conditions vis-à-vis waitlist comparison conditions at both post-treatment (effect size [ES] = 0.52, 95% CI [0.40, 0.64]) and follow-up (ES = 0.52 [0.20, 0.84]), although the effect at follow-up diminished to non-significance in a trim-and-fill analysis intended to account for publication bias (ES = 0.35 [− 0.03, 0.72]). Measures of mindfulness also showed relatively larger gains in mindfulness intervention conditions vis-à-vis bona fide comparison conditions, but only at post-treatment (ES = 0.25 [0.11, 0.38], 0.10 [− 0.08, 0.28], at post-treatment and follow-up, respectively). All three conditions (mindfulness, bona fide, waitlist) showed relatively larger improvements on measures of clinical outcomes than measures of mindfulness, with the exception of waitlist conditions for which this effect was no longer significant at follow-up. Taken together, findings provide partial support for the unique responsiveness of mindfulness self-report measures to interventions that include promotion of mindfulness meditation practice.

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Funding

This work was funded by the National Center for Complementary and Alternative Medicine (Grant P01AT004952) and the Mind & Life Institute (Francisco J. Varela Award). NCCAM and Mind and Life Institute were not directly involved in study design; collection, analysis, or interpretation of data; in writing of the report; or in the decision to submit the article for publication. Any views, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect those of the Mind & Life Institute.

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Correspondence to Simon B. Goldberg.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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RD is the founder, president, and serves on the board of directors for the non-profit organization, Healthy Minds Innovations, Inc. In addition, RD serves on the board of directors for the Mind and Life Institute. The remaining authors (SG, RT, PG, TS, WH, DK) declare that they have no conflict of interest.

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Goldberg, S.B., Tucker, R.P., Greene, P.A. et al. What Can We Learn from Randomized Clinical Trials About the Construct Validity of Self-Report Measures of Mindfulness? A Meta-Analysis. Mindfulness 10, 775–785 (2019). https://doi.org/10.1007/s12671-018-1032-y

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