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Table 2 Different functionalized palladium nanoparticles used for cancer treatment

From: Palladium Nanoparticles as a Platform for Cancer Diagnosis and Treatment

Sr no

Pd NPs/functionalization

Size

Type of cancer

Combination therapy with PdNPs

References

1

FA-CS-R-Pd NCs

 < 100 nm

Breast cancer –

MBA MB 231 cells

PTT

[24]

2

TMC/PdNPs

2–20 nm

Breast cancer

MBA MB 231 cells

PTT

[25]

3

Au@Pd NDs DOX nanocarrier

 < 100 nm

Breast cancer –

MCF-7 cells

Chemotherapy

[26]

4

PVP-PdNPs

9–15 nm

Breast cancer –

MCF-7 cells

Chemotherapy

[27]

5

PCN-224@Pd/H2

 > 10 nm

Breast cancer –

MDA-MB-231

PDT

[28]

6

PtPd-PEG-FA-DOX

 

Breast cancer –

MCF-7 cells

PTT + Chemotherapy

[29]

7

Pd@COS-RGP

23.54 ± 1.25 nm

Breast cancer –

MDA-MB-231 cells

PTT

[30]

8

PdNPs/GDY

3.1 nm

Lung cancer –

A549 cells

Chemo-catalytic therapy

[31]

9

Melatonin/PdNPs

10 nm

Lung cancer –

A549 cells

Chemotherapy

[32]

10

Pd NPs

13–33 nm

Lung cancer –

A549 cells

 

[33]

11

C. guianensis–reduced PdNPs

5–15 nm

Lung cancer –

A549 cells

Phytochemical based therapy

[34]

12

Aloe vera gel reduced Pd@TiO2

11 nm

Lung cancer –

A549 cells

Phytochemical based therapy

[35]

13

Terminalia chebula–reduced AgPd NPs

20 nm

Lung cancer –

A549 cells

Phytochemical based therapy

[36]

14

PdNS-CpG

5 and 20 nm

Murine cells –

RAW 264.7

Immunotherapy

[37]

15

Pd-HA NPs + 

Pd-M@R NPs

28.2–45 nm

Colon cancer –

CT26 and RAW 264.7 cells

Chemodynamic therapy

[38]

17

Pd-Dox@ triglycerol monostearates NPs

16.2 ± 1.9 nm

Colon cancer –

CT26 cells

PTT + Chemotherapy

[39]

18

PtAu/PdAu NPs

5–20 nm

Colon cancer –

SW480, SW620, and HCT116 cells

Radiotherapy

[40]

19

AuPd@PVP NPs

20–40 nm

Colon cancer –

MC-38 cells

PTT + radiosensitivity

[41]

20

Pd/chitosan/reduced graphene oxide

4–6 nm

Colon cancer –

HT-29 cells

Chemotherapy

[42]

21

Urtica-reduced PdNPs

7.44 ± 1.94 nm

Colon cancer –

HT-29 cells

Phytochemical based therapy

[43]

22

Saussurea costus–reduced PdNPs

1.9 to 17.6 nm

Colon cancer –

HCT-116 cells

Phytochemical based therapy

[44]

23

PdNPs-PVP-Quercetin

2.3 to 8.29 nm

Colon cancer –

HCT-15 cells

Phytochemical based therapy

[45]

24

CuCO2S4–Pd/DOX/TD

8.9 nm

Cervical cancer –

HeLa cells

PTT + chemotherapy

[46]

25

Lan -PdNPs@GSH/DOX

138.4 ± 5.0 nm

Cervical cancer –

HeLa cells

PTT + chemotherapy

[47]

26

PdCs–HSA–ICG

110 nm

Cervical cancer –

HeLa cells

PTT + PDT

[48]

27

Inonotus obliquus–reduced PdNPs

77–92 nm

Cervical cancer –

HeLa cells

PTT + phytochemical + chemotherapy

[49]

28

Hesperidin-reduced PdNPs

10 nm

Ovarian cancer –

SKOV3 cells

Chemotherapy

[50]

29

PEG-SH-Pd@Pt

16–19 nm

Osteosarcoma –

LM8 cells

PTT + PDT

[51]

30

Graphene oxide-PdNPs

 < 200 nm

Prostate cancer –

PC3 cells

PTT

[52]