Fabrication of Magnetically Responsive Agarose Microbeads Doped with Live Microbial Cells


Here, we report a scalable and rapid method to fabricate magnetically responsive agarose microgels doped with microbial cells. Low-temperature melting agarose and food-grade sunflower oil were used to fabricate microbeads during emulsification and gel setting. Microscopic algae and fungi cells were doped into ∼100-μm-sized beads as single culture or mixed. Magnetic nanoparticles were deposited either on cell walls or on bead walls. We found that the cells encapsulated in magnetically responsive microbeads were viable and able for germination.

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The work is performed according to the Russian Government Program of Competitive Growth of Kazan Federal University and funded by the subsidy allocated to Kazan Federal University for the state assignment in the sphere of scientific activities.

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Correspondence to Rawil Fakhrullin.

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Konnova, S., Fakhrullin, R. Fabrication of Magnetically Responsive Agarose Microbeads Doped with Live Microbial Cells. BioNanoSci. 7, 75–77 (2017). https://doi.org/10.1007/s12668-016-0301-2

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  • Encapsulation
  • Magnetic functionality
  • Viability
  • Agarose