Skip to main content

Advertisement

SpringerLink
Log in

The Use of Hydrogel/Silver Nanoparticle System for Preparation of New Type of Feminine Tampons

  • Published:
BioNanoScience Aims and scope Submit manuscript

Abstract

This research deals with the synthesis of chitosan/polyvinyl alcohol/polyethylene glycol/silver nanoparticle composite via gamma-irradiation technique. The reduction of silver nitrate, formation of Ag nanoparticles, cross-linking of hydrogel network, and modification of cotton tampon with this antibacterial/absorbing system were occurred simultaneously. The size distribution of the composite system and the morphology of the synthesized particles and the modified cotton fibers were examined by particle size analyzer and FE-SEM techniques. X-ray diffraction detected the presence of cubic structure of silver nanoparticles in hydrogel system. The results of dynamic light scattering (DLS) showed that the average size of composite system was around 96 nm. The modified tampons absorbed more water and simulated body fluid than untreated sample (2.06 and 1.39 times, respectively) and had excellent antibacterial effect (above 90 %), against Staphylococcus aureus bacteria, the main reason for toxic shock syndrome. The dermal toxicity tests did not show erythema or edema in macroscopic observations on the skin of rabbits during the entire 5-day in vivo study. The results presented could upgrade the regular feminine cotton tampon quality by providing attractive feature.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. Cheyne, W. W. (1885). Manual of the antiseptic treatment of wounds: for students and practitioners. New York: J.H. Vail.

    Google Scholar 

  2. Madan, R. K., & Levitt, J. (2014). A review of toxicity from topical salicylic acid preparations. Journal of the American Academy of Dermatology, 70, 788–792.

    Article  Google Scholar 

  3. Anzala, O. A., et al. (1996). Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection. The Journal of Infectious Diseases, 173, 6686–6689.

    Google Scholar 

  4. Dinges, M. M., Orwin, P. M., Schlievert, P. M. (2000). Exotoxins of Staphylococcus aureus. Clinical Microbiology Reviews, 13, 16–34.

    Article  Google Scholar 

  5. Bashari, A., Hemmati Nejad, N., Pourjavadi, A. (2013). Applications of stimuli responsive hydrogels: a textile engineering approach. Journal of the Textile Institute, 104, 1145–1155.

    Article  Google Scholar 

  6. Hennink, W. E., & van Nostrum, C. F. (2002). Novel crosslinking methods to design hydrogels. Advanced Drug Delivery Reviews, 54, 13–36.

    Article  Google Scholar 

  7. Barbucci, R., Leone, G., Vecchiullo, A. (2004). Novel carboxymethylcellulose-based microporous hydrogels suitable for drug delivery. Journal of Biomaterials Science Polymer Edition, 15, 607–619.

    Article  Google Scholar 

  8. Said, H. M., Abd Alla, S., El-Naggar, A. W. M. (2004). Synthesis and characterization of novel gels based on carboxymethyl cellulose/acrylic acid prepared by electron beam irradiation. Reactive and Functional Polymers, 61, 397–404.

    Article  Google Scholar 

  9. Bin, F., et al. (2000). Hydrogel of biodegradable cellulose derivatives I. Radiation-induced crosslinking of CMC. Journal of Applied Polymer Science, 78, 278–283.

    Article  Google Scholar 

  10. Liu, P., et al. (2002). Radiation preparation and swelling behavior of sodium carboxymethyl cellulose hydrogels. Radiation Physics and Chemistry, 63, 525–528.

    Article  Google Scholar 

  11. Shahverdi, A. R., et al. (2007). Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli. Nanomed-Nanotechnol, 3, 168–171.

    Article  Google Scholar 

  12. Rai, M., Yadav, A., Gade, A. (2009). Silver nanoparticles as a new generation of antimicrobials. Biotechnology Advances, 27, 76–83.

    Article  Google Scholar 

  13. Cho, S. B. N., et al. (1995). Dependence of apatite formation on silica gel on its structure: effect of heat treatment. Journal of the American Ceramic Society, 78, 1769–1774.

    Article  Google Scholar 

  14. Singh, G., et al. (2012). Evaluation of antibacterial activity of ZnO nanoparticles coated sonochemically onto textile fabrics. JMBFS, 2, 106–120.

    Google Scholar 

  15. Erdem, A., & Sanli, N. (2008). The evaluation of antibacterial activity of fabrics impregnated with dimethyltetradecyl (3-(trimethoxysilyl) propyl) ammonium chloride. IUFS Journal of Biology, 67, 115–122.

    Google Scholar 

  16. Gasaymeh, S. S., et al. (2010). Synthesis and characterization of silver/poly vinil pirrolidone (Ag/PVP) nanoparticles using gamma irradiation techniques. American Journal of Applied Sciences, 7, 892–901.

    Article  Google Scholar 

  17. Salehi, A. H., Montazer, M., Toliyat, T. (2014). Synthesis and characterization of Au:Ag nanoparticles using trisodium citrate and SDS. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 44, 1421–1425.

    Article  Google Scholar 

  18. Salehi, A. H., et al. (2015). A new route for synthesis of silver:gold alloy nanoparticles loaded within phosphatidylcholine liposome structure as an effective antibacterial agent against Pseudomonas aeruginosa. Journal of Liposome Research, 25, 38–45.

    Article  Google Scholar 

  19. Lu, Z., et al. (2013). Size-dependent antibacterial activities of silver nanoparticles against oral anaerobic pathogenic bacteria. Journal of Materials Science Materials in Medicine, 24, 1465–1471.

    Article  Google Scholar 

  20. Karim, M. R., et al. (2007). Synthesis of core‐shell silver–polyaniline nanocomposites by gamma radiolysis method. Journal of Polymer Science, A1(45), 5741–5747.

    Google Scholar 

  21. Nikolic, V. M., et al. (2007). On the use of gamma irradiation crosslinked PVA membranes in hydrogen fuel cells. Electrochemistry Communications, 9, 2661–2665.

    Article  Google Scholar 

  22. Baker, M. I., et al. (2012). A review of polyvinyl alcohol and its uses in cartilage and orthopedic applications. Journal of Biomedical Materials Research. Part B, Applied Biomaterials, 100B, 1451–1457.

    Article  Google Scholar 

  23. Mansor Bin Ahmad, M. Y. T., et al. (2011). Green synthesis and characterization of silver/chitosan/polyethylene glycol nanocomposites without any reducing agent. International Journal of Molecular Sciences, 12, 4872–4884.

    Article  Google Scholar 

  24. Venkatesham, M., et al. (2014). A novel green one-step synthesis of silver nanoparticles using chitosan: catalytic activity and antimicrobial studies. Applied Nanoscience, 4, 113–119.

    Article  Google Scholar 

  25. Huang, H., Yuan, Q., Yang, X. (2004). Preparation and characterization of metal–chitosan nanocomposites. Colloid Surface B, 39, 31–37.

    Article  Google Scholar 

  26. Shkilnyy, A., et al. (2009). Poly(ethylene glycol)-stabilized silver nanoparticles for bioanalytical applications of SERS spectroscopy. Analyst, 134, 1868–1872.

    Article  Google Scholar 

  27. Cui, J., et al. (2012). Synthetically simple highly resilient hydrogels. Biomacromolecules, 13, 584–588.

    Article  Google Scholar 

  28. Virk, H. S., & Srivastava, A. K. (2001). Modification of optical, chemical and structural response of CR-39 polymer by 50 MeV lithium ion irradiation. Radiation Measurements, 34, 65–67.

    Article  Google Scholar 

  29. Lugao, A. B., & Malmonge, S. M. (2001). Use of radiation in the production of hydrogels. Nucl Instrum Meth B, 185, 37–42.

    Article  Google Scholar 

  30. Ahmed, E. M. (2015). Hydrogel: preparation, characterization, and applications: a review. Journal of Advance Research, 6, 105–121.

    Article  Google Scholar 

  31. Khan, F., Ahmad, S. R., Kronfli, E. (2006). γ-radiation induced changes in the physical and chemical properties of lignocellulose. Biomacromolecules, 7, 2303–2309.

    Article  Google Scholar 

  32. Buzea, C., Pacheco, I., Robbie, K. (2007). Nanomaterials and nanoparticles: sources and toxicity. Biointerphases, 2, MR17–MR71.

    Article  Google Scholar 

  33. Rejane, C. G., et al. (2009). A review of the antimicrobial activity of chitosan. Polímeros: Ciência e Tecnologia, 19, 241–247.

    Article  Google Scholar 

Download references

Acknowledgment

This research was supported by a grant from ENT-HNS Research Center at Iran University of Medical Sciences (IUMS).

Author information

Authors and Affiliations

  1. Medical Physics Department, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran

    Ali Shakeri-Zadeh

  2. Textile Engineering Department, Amirkabir University of Technology, Tehran, Iran

    Azadeh Bashari

  3. Clinical Nanomedicine Lab, ENT and Head & Neck Research Center and Department, Iran University of Medical Sciences (IUMS), Tehran, Iran

    Ali Shakeri-Zadeh & Seyed Kamran Kamrava

  4. Medical Engineering Department, Islamic Azad University, South Tehran Branch, Tehran, Iran

    Suzan Ghalehbaghi

Authors
  1. Ali Shakeri-Zadeh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Azadeh Bashari
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Seyed Kamran Kamrava
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Suzan Ghalehbaghi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Azadeh Bashari or Suzan Ghalehbaghi.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Shakeri-Zadeh, A., Bashari, A., Kamrava, S.K. et al. The Use of Hydrogel/Silver Nanoparticle System for Preparation of New Type of Feminine Tampons. BioNanoSci. 6, 284–292 (2016). https://doi.org/10.1007/s12668-016-0220-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12668-016-0220-2

Keywords

Search

Navigation