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The prevalence of uninvestigated dyspepsia and the association of physical exercise with quality of life of uninvestigated dyspepsia patients in Indonesia: An internet-based survey

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Abstract

Background

Epidemiological data on the prevalence of uninvestigated dyspepsia (UD) and its impact on the health-related quality of life (HRQOL) in Indonesian population are still lacking. There is no study investigating the association between exercise and the HRQOL in UD patients. We aimed to investigate the prevalence of UD and its association with physical exercise, and its impact on HRQOL in Indonesian patients with UD.

Methods

This was a population-based, cross-sectional study, conducted using an internet-based questionnaire which was randomly distributed throughout Indonesia using the social media. The questionnaire contained socio-demographic details, exercise levels, Rome III criteria for dyspepsia, and SF-NDI (Short Form-Nepean Dyspepsia Index). The frequency, duration, the intensity of exercise, and the classification of exercise according to ACSM (American College of Sports Medicine) were included in the assessment. The screening for UD was conducted using the Rome III criteria and the SF-NDI score was calculated to assess the HRQOL in patients with UD.

Results

A total of 2725 valid responses were collected. The overall prevalence of UD in the study was 49.75%. Multiple logistic regression analysis showed that gender (female) and lack of exercise were independently associated with UD (OR 2.07, 95% CI 1.74–2.47, p < 0.001 and OR 1.72, 95% CI 1.42–2.07, p < 0.001). The median SF-NDI score among 1295 UD subjects in non-exercising and exercising groups was 21.00 and 18.00 (p < 0.001), respectively.

Conclusion

This study demonstrated the prevalence of UD and the association between exercise and HRQOL among UD patients in Indonesia.

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Author notes

  1. Ian Huang and Raymond Pranata contributed equally to this work.

Authors and Affiliations

  1. Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Banten, Indonesia

    Ian Huang, Raymond Pranata, Winfrey Pangestu, Felicia Nathania Kosasih & Wilson Matthew Raffaello

  2. Internal Medicine Department, Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia

    Theo Audi Yanto & Nata Pratama Hardjo Lugito

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  1. Ian Huang
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Contributions

IH and RP conceived and drafted the study design. IH, RP, WP, WMR, and FNK collected all data. IH, RP, TAY, and NPHL analyzed and interpreted the data. IH, RP, WP, FNK, and WMR prepared the manuscript draft. TAY and NPHL supervised and gave expert advice. All authors commented on drafts of the paper. All authors have approved the final draft of the manuscript. IH is the guarantor.

Corresponding author

Correspondence to Ian Huang.

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Competing interests

IH, RP, WP, FNK, WMR, TAY, and NPHL declare that they have no competing interests.

Ethics statement

The study was performed conforming to the Helsinki declaration of 1975, as revised in 2000 and 2008 concerning human and animal rights, and the authors followed the policy concerning informed consent as shown on Springer.com.

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Huang, I., Pranata, R., Pangestu, W. et al. The prevalence of uninvestigated dyspepsia and the association of physical exercise with quality of life of uninvestigated dyspepsia patients in Indonesia: An internet-based survey. Indian J Gastroenterol 40, 176–182 (2021). https://doi.org/10.1007/s12664-020-01113-z

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  • DOI: https://doi.org/10.1007/s12664-020-01113-z

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