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Indian Journal of Gastroenterology

, Volume 37, Issue 1, pp 74–75 | Cite as

Role of noninvasive markers to predict the presence of esophageal varices in cirrhosis: Pilot study

  • Vijayanand Kumar Vegiraju
  • Shiran Shetty
  • Venkatakrishnan Leelakrishnan
  • Krishnaveni Janarthanan
  • Naveen Mohandas
  • Devanand Balakshmoji
Letter
  • 71 Downloads

Cirrhosis of liver leads to portal hypertension and development of esophageal varices (EV), rupture of which results in spontaneous hematemesis. Upper gastrointestinal (UGI) bleeding is a catastrophic presentation of EV. Endoscopy remains the standard procedure for diagnosis [1] and esophageal variceal ligation as treatment of varices for decades; but with each passing day, the demand to develop noninvasive methods to diagnose varices is increasing. This pilot study aimed to find the association between esophageal varices, liver stiffness, spleen stiffness, and platelet counts and also to assess whether these indicators can be used to establish benchmarks in the future as noninvasive predictors of portal hypertension.

A cross-sectional observational study was done at a tertiary health center from February 2014, to January 2015. Adult patients of ages ≥ 18 years of either sex with newly diagnosed chronic liver disease (CLD) and portal hypertension were included. The patients underwent...

Notes

Compliance with ethical standards

Conflict of interest

VKV, SS, VL, KJ, NM, and DB declare that they have no conflict of interest.

References

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    Baig WW, Nagaraja MV, Varma M, Prabhu R. Platelet count to spleen diameter ratio for the diagnosis of esophageal varices: is it feasible? Can J Gastroenterol. 2008;22:825–8.CrossRefPubMedPubMedCentralGoogle Scholar
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Copyright information

© Indian Society of Gastroenterology 2018

Authors and Affiliations

  • Vijayanand Kumar Vegiraju
    • 1
  • Shiran Shetty
    • 2
  • Venkatakrishnan Leelakrishnan
    • 1
  • Krishnaveni Janarthanan
    • 1
  • Naveen Mohandas
    • 1
  • Devanand Balakshmoji
    • 3
  1. 1.Department of GastroenterologyPSG Institute of Medical Sciences and ResearchCoimbatoreIndia
  2. 2.Department of Gastroenterology and Hepatology, Kasturba Medical CollegeManipal UniversityManipalIndia
  3. 3.Department of RadiodiagnosisPSG Institute of Medical Sciences and ResearchCoimbatoreIndia

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