Abstract
Introduction
The prevalence of maxillary mucormycosis has surged in the wake of the COVID-19 pandemic. This study assesses the effectiveness of zygomatic implants and patient-specific 3D-manufactured implants in maxillary reconstruction post-mucormycosis secondary to COVID-19.
Methodology
Ten patients underwent surgical and prosthetic maxillary reconstruction utilizing zygomatic implants and patient-specific implants. Parameters including pain, implant exposure, infection, wound dehiscence, implant fit, post-operative surgical rating scale, oro-antral communication, facial edema, and orbital status were evaluated at baseline, 6 months, and 12 months post-surgery.
Results
Statistical analysis revealed a positive association using SPSS version 20. Zygomatic implants combined with patient-specific implant systems demonstrated efficient therapeutic outcomes for maxillary reconstruction, within the limitations of the study.
Conclusion
The study concludes that the integration of patient-specific implant systems with zygomatic implants offers a promising therapeutic approach for maxillary reconstruction post-mucormycosis secondary to COVID-19. However, further research with larger sample sizes and extended follow-up periods is warranted to validate these findings.
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References
Spagnuolo G, De Vito D, Rengo S, Tatullo M (2020) COVID-19 outbreak: an overview on dentistry. Int J Environ Res Public Health 17(6):2094
Gupta A, Sharma A, Chakrabarti A (2021) The emergence of post-COVID-19 mucormycosis in India: Can we prevent it? Indian J Ophthalmol 69(7):1645
Meher R, Wadhwa V, Kumar V, Shisha Phanbuh D, Sharma R, Singh I, Rathore PK, Goel R, Arora R, Garg S, Kumar S, Kumar J, Agarwal M, Singh M, Khurana N, Sagar T, Manchanda V, Saxena S (2022) COVID associated mucormycosis: a preliminary study from a dedicated COVID Hospital in Delhi. Am J Otolaryngol. 43(1):103220
Gopal A, Sharma R, Negi S et al (2022) Post-COVID mucormycosis of mandible: a conundrum of management. Cureus 14(7):e27382
Kumar JA, Babu P, Prabu K, Kumar P (2013) Mucormycosis in maxilla: rehabilitation of facial defects using interim removable prostheses: a clinical case report. J Pharm Bioallied Sci 5(Suppl 2):S163–S165
Manmadhachary A, Malyala SK, Kumar R, Reddy H, Alwala A (2017) Design & manufacturing of Implant for reconstructive surgery: a case study. KnE Eng 9:143–149
Ghantous Y, Nashef A, Mohanna A, Abu-El-naaj I (2020) Three-dimensional technology applications in maxillofacial reconstructive surgery: current surgical implications. Nanomaterials 10(12):2523
Truscott A, Zamani R, Akrami M (2022) Comparing the use of conventional and three-dimensional printing (3DP) in mandibular reconstruction. Biomed Eng Online 21(1):18
Prithviraj DR, Vashisht R, Bhalla HK (2014) From maxilla to zygoma: a review on zygomatic implants. J Dent Implants 4(1):44
Rosenstein J, Dym H (2020) Zygomatic implants: a solution for the atrophic maxilla. Dent Clin 64(2):401–409
Gulia S, Vigarniya MM (2017) A comprehensive review on zygomatic implants. J Health Allied Sci NU 7(04):043–048
Arafat Y, Kumar YN, Bharani K et al (2021) COVID-19-related mucormycotic osteomyelitis of the maxilla: a case report of findings, surgical management and post-surgical rehabilitation. World J Dent 12(5):423–426
Kim MM, Boahene KD, Byrne PJ (2009) Use of customized polyetheretherketone (PEEK) implants in the reconstruction of complete maxillofacial defects. Arch Facial Plast Surg 11(1):53–57
Owusu JA, Boahene K (2015) Update of patient-specific maxillofacial implant. Curr Opin Otolaryngol Head Neck Surg 23(4):261–264
Mitsuishi M, Cao J, Bártolo P, Friedrich D, Shih AJ, Rajurkar K, Sugita N, Harada K (2013) Biomanufacturing. CIRP Ann 62(2):585–606
Farré-Guasch E, Wolff J, Helder MN, Schulten EA, Forouzanfar T, Klein-Nulend J (2015) Application of additive manufacturing in oral and maxillofacial surgery. J Oral Maxillofac Surg 73(12):2408–2418
Kaushik AS, Balaji T, Alwala AM (2022) Design, analysis, and fabrication of patient-specific implant for maxillofacial surgery. Int J Sci Res Eng Manage 06(06):1–13
Grecchi F, Zecca PA, Macchi A, Mangano A, Riva F, Grecchi E, Mangano C (2020) Full-digital workflow for fabricating a custom-made direct metal laser sintering (DMLS) mandibular implant: a case report. Int J Environ Res Public Health 17(8):2693
Zoabi A et al (2022) 3D printing and virtual surgical planning in oral and maxillofacial surgery. J Clin Med 11(9):2385
Ghantous Y, Nashef A, Mohanna A, Abu-El-Naaj I (2020) Three-dimensional technology applications in maxillofacial reconstructive surgery: current surgical implications. Nanomaterials (Basel) 10(12):2523
Aparicio C, Manresa C, Francisco K, Claros P, Alández J, González-Martín O, Albrektsson T (2014) Zygomatic implants: indications, techniques and outcomes, and the zygomatic success code. Periodontology 2000 66(1):41–58
Chrcanovic BR, Abreu MH (2013) Survival and complications of zygomatic implants: a systematic review. Oral Maxillofac Surg 17(2):81–93
Sharma A, Rahul GR (2013) Zygomatic implants/fixture: a systematic review. J Oral Implantol 39:215–224
Chrcanovic BR, Albrektsson T, Wennerberg A (2016) Survival and complications of zygomatic implants: an updated systematic review. J Oral Maxillofac Surg 74(10):1949–1964
Wu YQ, Zhang ZY, Zhang ZY, Sun J, Huang W, Hu YJ, Zhang CP (2005) Zygomatic implants anchorage for the rehabilitation of maxillary defects. Shanghai Kou Qiang Yi Xue 14(3):210–214
Wang F, Monje A, Lin GH, Wu Y, Monje F, Wang HL, Davo R (2015) Reliability of four zygomatic implant-supported prostheses for the rehabilitation of the atrophic maxilla: a systematic review. Int J Oral Maxillofac Implants 30(2):293–298
Dominguez EA, Guerrero C, Shehata E, Van Sickels JE (2019) Zygoma implants or sinus lift for the atrophic maxilla with a dentate mandible: Which is the better option? Dental Clinics 63(3):499–513
Bedrossian E, Stumpel L III, Beckely M, Indersano T (2002) The zygomatic implant: preliminary data on treatment of severely resorbed maxillae. A clinical report. Int J Oral Maxillofac Implants 17(6):861–865
Malevez C, Daelemans P, Adriaenssens P, Durdu F (2003) Use of zygomatic implants to deal with resorbed posterior maxillae. Periodontology 2000 33(1):82–89
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Arvind, U.D., Gaddipati, R., Alwala, A.M. et al. Integrative Approach to Maxillary Reconstruction: Assessment of Proficiency of Zygomatic and 3D-Manufactured Patient-Specific Implants in Mucormycosis Post-COVID-19. J. Maxillofac. Oral Surg. (2024). https://doi.org/10.1007/s12663-024-02177-6
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DOI: https://doi.org/10.1007/s12663-024-02177-6