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Incidence of Mortality and Its Relation to Comorbidity in Ludwig’s Angina: A Retrospective Study

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Abstract

Introduction

Ludwig’s angina is a serious life-threatening infective condition of maxillofacial region due to odontogenic origin which is clinically diagnosed by its clinical signs and symptoms. Airway management and early surgical decompression is the main stay of management. The mortality rates in Ludwig’s angina remains multivariate. There is a paucity in literature regarding the mortality rates of this disease.

Aim and Objectives

Aim of this retrospective study is to describes the characteristics, probable cause of death and mortality rates of patients with co-morbidities presenting to the emergency department (ED) who were subsequently admitted with a primary diagnosis of Ludwig’s angina.

Materials and Method

Study was conducted in the department of maxillofacial surgery in a tertiary care teaching hospital from Jan 2011 to Dec 2022. Data of 17 patients who were clinically diagnosed as Ludwig’s angina were included in the study. The comorbidity, source of odontongenic cause, mode of intubation and the outcome of the disease were evaluated.

Result

Comparison of categorical variables was done using Fishers exact test. A p-value of <0.7 was considered statistically significant. The results suggested that Out of 17 patients 12 patients (70.5%), 7 male and 5 females had comorbidities and four cases (23.5%) had complication of death, all having co-morbidities.

Summary

It concludes that associated comorbidity has a significant role in progress and outcome of the disease and incidence of death is more common in cases having associated comorbidity.

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References

  1. SC Murphy 1996 The person behind the eponym: Wilhelm Frederick von Ludwig (1790–1865) J Oral Pathol Med 25 9 513 515

    Article  CAS  PubMed  Google Scholar 

  2. I Brook 2007 Microbiology and principles of antimicrobial therapy for head and neck infections Infect Dis Clin North Am 21 2 355 391

    Article  PubMed  Google Scholar 

  3. R Candamourty S Venkatachalam MR Babu GS Kumar 2012 Ludwig's Angina–an emergency: a case report with literature review J Nat Sci, Biol Med 3 2 206

    Article  PubMed  Google Scholar 

  4. DE Fritsch DG Klein 1992 Ludwig's angina Heart Lung 21 1 39 46

    CAS  PubMed  Google Scholar 

  5. SC Reynolds AW Chow 2007 Life-threatening infections of the peripharyngeal and deep fascial spaces of the head and neck Infect Dis Clin North Am 21 2 557 576

    Article  PubMed  Google Scholar 

  6. Marciani RD (1992) Clinical considerations in head and neck infections. In: Peterson LJ, Indresano AT, Marciani RD, Roser SM, (Eds). Principles of oral and maxillofacial surgery, Philadelphia, p. 175

  7. YK Chou CY Lee HH Chao 2007 An upper airway obstruction emergency: Ludwig’s angina Pediatr Emerg Care 23 12 892 896

    Article  PubMed  Google Scholar 

  8. LW Moreland J Corey R McKenzie 1988 Ludwig's angina: report of a case and review of the literature Arch Intern Med 148 2 461 466

    Article  CAS  PubMed  Google Scholar 

  9. A Sharp J Clark 2011 Diabetes and its effects on wound healing Nurs Stand 25 45 41 47

    Article  PubMed  Google Scholar 

  10. T Sarna T Sengupta M Miloro A Kolokythas 2012 Cervical necrotizing fasciitis with descending mediastinitis: literature review and case report J Oral Maxillofac Surg 70 6 1342 1350

    Article  PubMed  Google Scholar 

  11. ML Seer Yee N Abdul Rahim NA Ngah YF Abdul Aziz S Subha 2014 Predicting neck abscess with contrast-enhanced computed tomography Adv Otolaryngol 2 1 8

    Google Scholar 

  12. SC Bagheri 2014 Clinical review of oral and maxillofacial surgery: a case-based approach 2 Mosby Elsevier St. Louis 95 118

    Google Scholar 

  13. MH Ohn R Wadhwa 2023 Angioneurotic edema StatPearls Publishing Treasure Island, FL

    Google Scholar 

  14. SW Neff A Merry B Anderson 1999 Airway management in Ludwig's angina Anaesth Intens Care 27 6 659 661

    Article  CAS  Google Scholar 

  15. SC Bagheri RB Bell HA Khan 2011 Current therapy in oral and maxillofacial surgery Elsevier Philadelphia 1092 1098

    Google Scholar 

  16. A Tami S Othman A Sudhakar BJ McKinnon 2020 Ludwig's angina and steroid use: a narrative review Am J Otolaryngol 41 3 102

    Article  Google Scholar 

  17. S Kent B Dawoud A Henry 2022 Stress hyperglycaemia or diabetes mellitus in cervicofacial infections? A maxillofacial surgery trainee research collaborative (MTReC) study Br J Oral Maxillofac Surg 60 8 1049 1055

    Article  Google Scholar 

  18. JA Mcdonnough DA Ladzekpo I Yi WR Bond Jr 2019 Epidemiology and resource utilization of Ludwig's angina ED visits in the United States 2006–2014 Laryngoscope 129 9 2041 2044

    Article  PubMed  Google Scholar 

  19. OD Osunde GO Bassey N Ver-Or 2014 Management of Ludwig’s angina in pregnancy: a review of 10 cases Ann Med Health Sci Res 4 3 361 364

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to N. K. Sahoo.

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Sahoo, N.K., Thakral, A., Pandey, S. et al. Incidence of Mortality and Its Relation to Comorbidity in Ludwig’s Angina: A Retrospective Study. J. Maxillofac. Oral Surg. (2024). https://doi.org/10.1007/s12663-024-02116-5

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  • DOI: https://doi.org/10.1007/s12663-024-02116-5

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