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Maxillary Bone Microstructure After Lateral Sinus Flour Augmentation with Deproteinized Bovine Bone Material in Severe Alveolar Bone Atrophy: Comparative Micro-CT Study

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Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Background

The most common material used for lateral sinus floor augmentation (LSFA) is xenogenic deproteinized bovine bone (DBB). However, in cases with significantly decreased residual bone height (RBH) (2–3 mm or less) where the osteogenic potential and vasculature of the recipient area are compromised the efficacy of the DBB is debatable. The aim of the study was to investigate the structural properties of the subantral bone regenerate by micro-CT in patients treated for significant alveolar ridge atrophy (RBH less than 3 mm) with LSFA and DBB grafts.

Materials and Methods

Twenty patients (10 men and 10 women) were included in the study and divided into two groups: (1) the main group–10 patients with edentulous posterior maxilla and RBH less than 3 mm, where LSFA was performed to create the appropriate bone volume for installation of the implants; (2) the control group–10 patients with RBH more than 10 mm and no necessity for bone augmentation procedures. In all patients, the bone samples were taken during the insertion of the implants in the area of interest. All samples were analyzed by micro-CT method. 3-D morphometric parameters were evaluated and compared in both groups.

Results

There were no significant differences in parameters that reflected 3-D morphometric structure and density of the edentulous alveolar bone with sufficient bone volume and augmented bone in patients with RBH less than 3 mm (p > 0.05). The slight differences were observed in trabecular architecture: In operated patients, the lower porosity, bone volume-to-surface ratio, anisotropy rate and increased trabecular pattern factor as a result of continuous functional remodeling process were observed.

Conclusion

Maxillary sinus floor elevation with DBB alone is a strategy, providing an appropriate 3-D architecture of the newly formed bone tissue and adequate primary stability of the dental implants. The biological properties and long-term remodeling of the augmented bone in patients of this category requires the further investigation.

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Acknowledgment

The project No. TKP2021-NVA-07 and TKP2021-EGA-13 have been implemented with the support provided from the National Research, Development and Innovation Fund of Hungary, financed under the TKP2021-NVA and TKP2021-EGA funding schemes.

Funding

This work was supported by a research grant from the Ministry of Health of Ukraine (state registration number 0122U001339).

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Authors and Affiliations

  1. Department of Maxillofacial Surgery and Innovative Dentistry, Bogomolets National Medical University, 13, T. Shevchenko blvd, Kyiv, 01601, Ukraine

    Oleksandr Shpachynskyi & Andrii Kopchak

  2. Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti Str. 12, Pécs, 7624, Hungary

    Tamás Kiss

  3. PharmInVivo Ltd, Szondi Gy. U. 7, Pécs, 7629, Hungary

    Zsuzsanna Helyes

Authors
  1. Oleksandr Shpachynskyi
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  2. Tamás Kiss
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  3. Zsuzsanna Helyes
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  4. Andrii Kopchak
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Contributions

AK, OS contributed to conception and design, analysis and interpretation of data, drafting the article. OS, TK contributed to data collection, analysis and interpretation of data. AK, ZH critically revised the article and supervised the study.

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Correspondence to Oleksandr Shpachynskyi.

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The authors declare no conflict of interest. The founders had no role in the design of the study, in the collection, analyses, or interpretation of data, in the writing of the manuscript, or in the decision to publish the results.

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Shpachynskyi, O., Kiss, T., Helyes, Z. et al. Maxillary Bone Microstructure After Lateral Sinus Flour Augmentation with Deproteinized Bovine Bone Material in Severe Alveolar Bone Atrophy: Comparative Micro-CT Study. J. Maxillofac. Oral Surg. (2024). https://doi.org/10.1007/s12663-024-02113-8

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