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Spontaneous Bone Neo-formation After Mandibular Resection: Case Report and a Scoping Review

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Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Background

Mandibular tumors in children are mostly benign, although they can be locally aggressive and rapidly progressing. Methods of reconstructing mandibular defects after the ablation of these lesions are still challenging. In the pediatric population, there is enormous periosteal osteogenic potential due to high cellular activity and viability of mesenchymal cells for new bone formation, which, together with grafts, can aid in spontaneous bone neo-formation (SBNF).

Case Report

We present an uncommon case of well-shaped bone neo-formation of the ramus–condyle unit in a 3-year-old patient who underwent mandibular partial resection after being affected by a central giant cell granuloma. In addition, a literature review of all the main cases of SBNF after partial or total resection of this bone is presented, with the representative features outlined.

Conclusion

Future studies focusing on the exact mechanisms of the periosteum in bone neo-formation should be conducted.

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Acknowledgements

Division of Oral Pathology—Department of Oral Diagnosis, Piracicaba Dental School, Campinas State University—FOP-UNICAMP in conducting the immunohistochemical analysis and final characterization of the lesion. The Information Technology Center—CTI Renato Archer (Campinas-SP) for planning and providing the prototyped biomodel.

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Authors and Affiliations

  1. Federal University of Maranhao Hospital, Rua Barão de Itapari, 227, Centro, São Luis, MA, 65020-070, Brazil

    André Luís Costa Cantanhede & Roque Soares Martins Neto

  2. Division of Oral Pathology, Federal University of Maranhao UFMA, São Luis, MA, Brazil

    Erika Martins Pereira

  3. Division of Oral and Maxillofacial Surgery, Federal University of Maranhao Hospital - HUUFMA, São Luis, MA, Brazil

    Eider Guimarães Bastos & Luis Raimundo Serra Rabelo

Authors
  1. André Luís Costa Cantanhede
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  2. Roque Soares Martins Neto
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  4. Eider Guimarães Bastos
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  5. Luis Raimundo Serra Rabelo
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Correspondence to André Luís Costa Cantanhede.

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This study was approved by the Federal University of Maranhao Ethical Committee (Protocol # 3.809.800).

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Cantanhede, A.L.C., Martins Neto, R.S., Pereira, E.M. et al. Spontaneous Bone Neo-formation After Mandibular Resection: Case Report and a Scoping Review. J. Maxillofac. Oral Surg. (2024). https://doi.org/10.1007/s12663-023-02084-2

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