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Is the Prevalence of Vitamin D deficiency in Patients with Temporomandibular Disorder Higher than Healthy Control Group?

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Abstract

Purpose

Vitamin D plays an essential role in subchondral bone, cartilage, and periarticular muscle. This study aims to assess the prevalence of vitamin D deficiency in temporomandibular disorder (TMD) patients.

Materials and methods

This is a cross-sectional study. Subjects were assigned into two groups based on having signs and symptoms of TMD: Group 1: subjects had TMD, and group 2 healthy group (control group). The serum level of vitamin D was measured in the two groups. The independent t test was used to compare the serum level of vitamin D between the study and control groups.

Results

One hundred ten subjects were studied into two groups (55 subjects in each group). The mean serum level of vitamin D was 18.13 ± 6.38 ng/mL in the study group and 31.83 ± 7.00 ng/mL in the control group. Analysis of the data demonstrated a significant difference in the mean serum level of vitamin D between the study and control groups (p = 0.001).

Conclusion

It seems the serum level of vitamin D is lower in TMD patients than in the healthy control group.

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References

  1. Janal MN, Raphael KG, Nayak S, Klausner J (2008) Prevalence of myofascial temporomandibular disorder in US community women. J Oral Rehabil 35(11):801–809

    Article  CAS  Google Scholar 

  2. Ryan J, Akhter R, Hassan N, Hilton G, Wickham J, Ibaragi S (2019) Epidemiology of temporomandibular disorder in the general population: a systematic review. Adv Dent Oral Health 10(3):1–13

    Google Scholar 

  3. Shen M, Luo Y, Niu Y, Chen L, Yuan X, Goltzman D, Miao D (2013) 1, 25 (OH) 2D deficiency induces temporomandibular joint osteoarthritis via secretion of senescence-associated inflammatory cytokines. Bone 55(2):400–409

    Article  CAS  Google Scholar 

  4. Zhang FF, Driban JB, Lo GH, Price LL, Booth S, Eaton CB et al (2014) Vitamin D deficiency is associated with progression of knee osteoarthritis. J Nutr 144(12):2002–2008

    Article  CAS  Google Scholar 

  5. Khanna SS, Parulekar NR, Dhaimade PA (2017) The influence of vitamin D on the temporomandibular joint and the activities of daily living. J ClinDiagnost Res 11(11):31–34

    Google Scholar 

  6. Yildiz S, Tumer MK, Yigit S, Nursal AF, Rustemoglu A, et al. Relationship of Vitamin D and Bsml variant with Temporomandibular Diseases in Turkish population. Br J Oral Maxillofac Surg. Doi: https://doi.org/10.1016/j.bjoms.2020.08.101

  7. Singh R, Kaur S (2018) Etiology of temporomandibular disorder-a brief review: part I. J Adv Med Dental Sci Res 6(10):78–81

    Google Scholar 

  8. Garfinkel RJ, Dilisio MF (2017) Agrawal DKJOJoSM. Vitamin D Effects Articular CartilOsteoarthr 5(6):2325967117711376

    Google Scholar 

  9. Staniszewski K, Lygre H, Berge T, Rosén AJPR (2019) Management Serum Analysis in Patients with Temporomandibular Disorders: a Controlled Cross-Sectional Study in Norway. Pain Res Manag. https://doi.org/10.1155/2019/1360725

    Article  Google Scholar 

  10. Demir CY, Ersoz ME (2019) Biochemical changes associated with temporomandibular disorders. J Int Med Res 47(2):765–771

    Article  CAS  Google Scholar 

  11. Gao XR, Chen YS, Deng W (2017) The effect of vitamin D supplementation on knee osteoarthritis: a meta-analysis of randomized controlled trials. Int J Surg 46:14–20

    Article  Google Scholar 

  12. Yu Y, Liu D, Feng D, Zhao J (2020) Association between vitamin D and knee osteoarthritis: a PRISMA-compliant meta-analysis. Z OrthopUnfall. https://doi.org/10.1055/a-1098-8815

    Article  Google Scholar 

  13. Heidari B, Heidari P, Hajian-Tilaki K (2011) Association between serum vitamin D deficiency and knee osteoarthritis. Int Orthop 35(11):1627–1631

    Article  Google Scholar 

  14. Vaishya R, Vijay V, Lama P, Agarwal A (2019) Does vitamin D deficiency influence the incidence and progression of knee osteoarthritis?—a literature review. J ClinOrthopaed Trauma 10(1):9–15

    Google Scholar 

  15. Bertoli FMDP, Bruzamolin CD, Pizzatto E, Losso EM, Brancher JA, de Souza JF (2018) Prevalence of diagnosed temporomandibular disorders: a cross-sectional study in Brazilian adolescents. PLoS ONE 13(2):e0192254

    Article  Google Scholar 

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Authors and Affiliations

  1. School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Majid Nemati, Reza Tabrizi, Faezeh Rasooli & Samin Ghafari

Authors
  1. Majid Nemati
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  2. Reza Tabrizi
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  3. Faezeh Rasooli
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  4. Samin Ghafari
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Contributions

RT, FR, and SG performed the research and documented subjects’ data. SN designed the study and analyzed and interpreted the patient data.

Corresponding author

Correspondence to Reza Tabrizi.

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Conflict of interest

The authors declare that they have no conflict of interests.

Ethics approval

The committee approved the study of the medical ethics group of Shahid Beheshti University of Medical Sciences. (IR.SBMU.DRC.REC.1398.100).

Consent to participate

All subjects signed a consent form to participate in the study.

Availability of data and material

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Nemati, M., Tabrizi, R., Rasooli, F. et al. Is the Prevalence of Vitamin D deficiency in Patients with Temporomandibular Disorder Higher than Healthy Control Group?. J. Maxillofac. Oral Surg. 21, 1205–1208 (2022). https://doi.org/10.1007/s12663-021-01522-3

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  • DOI: https://doi.org/10.1007/s12663-021-01522-3

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