Skip to main content

Advertisement

SpringerLink
Log in

Cemento-Ossifying Fibroma in Maxillofacial Region: A Series of 16 Cases

  • Original Article
  • Published:
Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Introduction

Cemento-ossifying fibroma is considered as a benign osseous tumour, closely related to other lesions such as fibrous dysplasia and cementifying periapical dysplasia. These lesions occur in the second to the fourth decade of life. It is a bony tumour of maxilla and mandible of possibly odontogenic origin with aggressive behaviour and high tendency for recurrence. Radiologically, the lesion appearances varied ranging from radiolucent cyst-like appearance to mixed and/or radiopaque areas.

Aims and objectives

The article attempts to highlight the importance of clinical, imaging aspects and histopathology in diagnosis of cemento-ossifying fibroma along with management and long-term follow-up.

Materials and methods

This retrospective study was done on histologically diagnosed 16 fibro-osseous lesions. These patients were treated under general anaesthesia at our institute. The demographic data, radiographic features, and histopathologic findings were analysed and compared. The treatment and follow-up data were also recorded.

Results

Cemento-ossifying fibroma showed higher predilection for female than for male patients and with an equal number of cases reported in maxilla and mandible with no signs of recurrence in long-term follow-up of 15 years.

Conclusion

Complete surgical excision of cemento-ossifying fibroma comes out to be only effective treatment that gave satisfactory results and can be considered as a definitive treatment modality.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Abbreviations

COF:

Cemento-ossifying fibroma

OF:

Ossifying fibroma

CT:

Computed tomography

References

  1. Eversole LR, Leider AS, Nelson K (1985) Ossifying fibroma: a clinicopathologic study of sixty-four cases. Oral Surg Oral Med Oral Pathol 60:505–511

    Article  CAS  Google Scholar 

  2. Waldron CA (1985) Fibro-osseous lesions of the jaws. J Oral Maxillofac Surg 43:249–262

    Article  CAS  Google Scholar 

  3. Mitrani M, Remsen K, Lawson W, Biller HF (1988) Giant ossifying fibroma of the paranasal sinuses. Ear Nose Throat J 67:186–192

    CAS  PubMed  Google Scholar 

  4. Khanna JN, Andrade NN (1992) Giant ossifying fibroma. Case report on a bimaxillary presentation. Int J Oral Maxillofac Surg 21:233–235

    Article  CAS  Google Scholar 

  5. More C, Thakkar K, Asrani M (2011) Cemento-ossifying fibroma. Indian J Dent Res 22:352–355

    Article  Google Scholar 

  6. Jankowski DSM (2009) Ossifying fibroma: a systematic review. Dentomaxillofac Radiol 38:495–513

    Article  Google Scholar 

  7. Sridevi U, Jain A, Turagam N, Prasad MD (2016) Cemento-ossifying fibroma: a case report. Adv Cancer Prev 1:111

    Article  Google Scholar 

  8. Ram R, Singhal A, Singhal P (2012) Cemento-ossifying fibroma. Contemp Clin Dent 3:83–85

    Article  Google Scholar 

  9. Sarwar HG, Jindal MK, Ahmad SS (2008) Cemento-ossifying fibroma—a rare case. J Indian Soc Pedod Prev Dent 26:128–131

    Article  CAS  Google Scholar 

  10. Slootweg PJ, Panders AK, Koopmans R, Nikkels PG (1994) Juvenile ossifying fibroma. An analysis of 33 cases with emphasis on histopathological aspects. J Oral Pathol Med 23:385–388

    Article  CAS  Google Scholar 

  11. Kaushik SK, Haranal S, Naresh N (2015) Cemento-ossifying fibroma of the mandible: a benign but potentially destructive tumor. Oral Maxillofac Pathol J 6:561–564

    Google Scholar 

  12. Van Heerden WF, Raubenheimer EJ, Weis RG, Kreidler J (1989) Giant ossifying fibroma: a clinico-pathologic study of 8 tumors. J Oral Pathol Med 18:506–509

    Article  Google Scholar 

  13. Marx RE, Stern D (2012) Oral and maxillofacial pathology: a rationale for diagnosis and treatment, 2nd edn. Quintessence Publishing Co, Inc, China, pp 841–844

    Google Scholar 

  14. Waldron CA, Giansanti JS (1973) Benign fibro-osseous lesions of the jaws: a clinical-radiologic-histologic review of sixty-five cases. Oral Surg 35:340–350

    Article  CAS  Google Scholar 

  15. Titinchi F, Morkel J (2016) Ossifying fibroma: analysis of treatment methods and recurrence patterns. J Oral Maxillofac Surg 74(12):2409–2419

    Article  Google Scholar 

  16. Barberi A, Cappabianca S, Collela G (2003) Bilateral cement-ossifying fibroma of the maxillary sinus. Br J Radiol 76:279–280

    Article  CAS  Google Scholar 

  17. Eversole LR, Merrell PW, Strub D (1985) Radiographic characteristics of central ossifying fibroma. Oral Surg Oral Med Oral Pathol 59:522–527

    Article  CAS  Google Scholar 

  18. White SC, Pharoah MJ (2000) Oral radiology principles and interpretation, 4th edn. Mosby, Philadelphia, pp 444–471

    Google Scholar 

  19. Neville BW, Damm DD, Allen CM, dan Bouquot JE (2002) Oral and maxillofacial pathology, 2nd edn. W B Saunders Company, Philadelphia, pp 533–589

    Google Scholar 

  20. Mithra R, Baskaran P, Sathyakumar M (2012) Imaging in the diagnosis of cemento-ossifying fibroma: a case series. J Clin Imaging Sci 2:52

    Article  CAS  Google Scholar 

  21. Bala TK, Soni S, Dayal P, Ghosh I (2017) Cemento-ossifying fibroma of the mandible. A clinicopathological report. Saudi Med J 38(5):541–545

    Article  Google Scholar 

  22. Shafer WG, Hine MK, Levy BM (2009) Textbook of oral pathology, 6th edn. Elsevier, India, pp 126–155

    Google Scholar 

  23. Chatterjee A, Ajmera N, Singh A (2010) Peripheral cemento-ossifying fibroma of maxilla. J Indian Soc Periodontol 14:186–189

    Article  Google Scholar 

  24. Endo Y, Uzawa K, Mochida Y, Nakatsuru M, Shiiba M, Yokoe H et al (2003) Differential distribution of glycosaminoglycans in human cementifying fibroma and fibro-osseous lesions. Oral Dis 9:73–76

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Sri Guru Ram Das Institute of Dental Sciences and Research, Mall Mandi, GT Road, Amritsar, 143001, India

    Tejinder Kaur, Amit Dhawan, Ramandeep Singh Bhullar & Sakshi Gupta

Authors
  1. Tejinder Kaur
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Amit Dhawan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ramandeep Singh Bhullar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Sakshi Gupta
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tejinder Kaur.

Ethics declarations

Informed Consent

Patients in the study have given informed consent to participate in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kaur, T., Dhawan, A., Bhullar, R.S. et al. Cemento-Ossifying Fibroma in Maxillofacial Region: A Series of 16 Cases. J. Maxillofac. Oral Surg. 20, 240–245 (2021). https://doi.org/10.1007/s12663-019-01304-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12663-019-01304-y

Keywords

Search

Navigation