Abstract
Calibre persistent labial artery (CPLA) usually presents as an asymptomatic papule on the lower lip and can be easily misdiagnosed as a mucocele, haemangioma, venous lake, varix or fibroma. When it is ulcerated, squamous cell carcinoma is the most usual differential diagnosis. Here, we report a case of a 25-year-old woman with no previous relevant medical history who presented with a complaint of an asymptomatic, non-ulcerated, progressively growing nodule (over the last 5 months) on the upper lip. In this case, the diagnosis was made clinically and confirmed by immunohistochemical analysis. We conclude that clinicians should be aware of CPLA and it should be included in the differential diagnosis of labial mucosal papules. Sometimes, the immunohistochemical analysis is necessary to make a correct diagnosis.
References
Voth D (1962) Das architektonische Prinzip der Magearterien in seiner Bedeutung fur die Magenblutung. Zentralblatt fur Allgeemeine Pathologie und Pathologische Anatomie 103:553–554
Miko T, Adler P, Endes P (1980) Simulated cancer of the lower lip attributed to “caliber persistent artery”. J Oral Pathol 9:137–144
Marshall RJ, Leppard BJ (1985) Ulceration of the lip associated with “calibre persistent artery”. Br J Dermatol 113:757–760
Jaspers MT (1992) Oral caliber-persistent artery: unusual presentations of unusual lesions. Oral Surg Oral Med Oral Pathol 74:631–633
Miko T, Molnar P, Vereckei L (1983) Interrelationships of calibre persistent artery, chronic ulcer and squamous carcinoma of the lower lip. Histopathology 7:595–599
Howell JB, Freeman RG (2002) The potential peril from caliber-persistent arteries of the lips. J Am Acad Dermatol 46(2):256–259
Manganaro AM (1998) Caliber-persistent artery of the lip: case report. J Oral Maxillofac Surg 56:895–897
Lovas JGL, Goodday RHB (1993) Clinical diagnosis of caliber-persistent labial artery of the lower lip. Oral Surg Oral Med Oral Pathol 76:480
Piccione MJ, Manganaro AM, Almony JS (2010) Caliber-persistent labial artery: diagnosis and treatment—case report. J Oral Maxillofac Surg 68(8):1987–1989
Correa PH, Nunes LCC, Johann ACBR, Aguiar MCFD, Gomez RS, Mesquita RA (2007) Prevalence of oral hemangioma, vascular malformation and varix in a Brazilian population. Braz Oral Res 21:40–45
Neville B (2002) Oral and maxillofacial pathology. W.B. Saunders, Philadelphia, pp 14–15
Kutzner H (1993) Expression of the human progenitor cell antigen CD34 (HPCA-1) distinguishes dermatofibrosarcoma protuberans from fibrous histiocytoma in formalin-fixed, paraffin-embedded tissue. J Am Acad Dermatol 28:613–617
Westra WH, Gerald WL, Rosai J (1994) Solitary fibrous tumor. Consistent CD34 immunoreactivity and occurrence in the orbit. Am J Pathol 18:992–998
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Santagata, M., Maglione, M., Colella, G. et al. Calibre Persistent Labial Artery: Clinical Features and Immunohistochemistry Diagnosis. J. Maxillofac. Oral Surg. 14, 845–847 (2015). https://doi.org/10.1007/s12663-014-0740-7
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DOI: https://doi.org/10.1007/s12663-014-0740-7