Abstract
Objective
The purpose of this retrospective analysis is to document and discuss the features, treatment rendered and result of 25 histologically proven cases of ossifying fibromas of jaw bones operated by a single surgeon over a period of 10 years.
Materials and Methods
The records of ossifying fibroma were obtained from the archives of Oral and Maxillofacial Surgery at Maulana Azad Institute of Dental Sciences (MAIDS) from 2001 to 2011. Only those cases were included in the study where definitive surgery was performed based on clinical, radiological & histopathological features.
Results
Twenty-five patients were analyzed with a final diagnosis of ossifying fibroma comprising of 14 males (56 %) and 11 females (44 %). The age range was 11–45 years with a mean of 24.12 years. Mandible was involved in 72 % and maxilla in 28 % cases with a predominance of mandibular posterior [19 (76 %)] cases. The study showed similar findings in regard to clinical, radiographic & histological features of ossifying fibroma as compared to other studies. It also showed that the treatment rendered in the form of eneucleation, curettage or resection of the lesion depending on its stage and extent were adequate, as no recurrence has been reported till date.
Conclusion
Enucleation is preferred in small and well demarcated lesions. Curettage should be done in relatively large lesions with ill defined borders, not involving basal bone of mandible or cortical perforation. Resection should be reserved for aggressive and extensive cases with involvement of basal bone or perforation of cortices.
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References
Krammer IRH, Pindborg JJ, Shear M (1992) WHO international classification of tumors. Histological typing of odontogenic tumors, 2nd edn. Springer-Verlag, London, p 27
Kolomvos N, Nadia Theologie-lygidakis N, Christopoulos P, Iatrou I (2013) Benign fibro-osseous lesions of the jaws in children: a 12 year retrospective study. J Craniomaxillofac Surg (In Press, corrected proof). Available online Jan 2013. doi: 10.1016/j.jcms.2012.11.029
Eversole LR, Merrell PW, Strub D (1985) Radiographic characteristics of central ossifying fibroma. Oral Surg Oral Med Oral Pathol 59(5):522–527
De Vicente JC, Gonzalez S, Santamaria J, Madrigal B (1997) Non odontogenic tumors of the jaws: classification, behaviour and diagnosis. Med Oral 2(2):83–93
Commins DJ, Tolley NS, Milford CA (1998) Fibrous dysplasia and ossifying fibroma of the paranasal sinuses. J Laryngol Otol 112(10):964–968
Martin-Granizo R, Sanchez-Cuellar A, Falahat F (2000) Cemento ossifying fibroma of the upper gingivae. Otolaryngol Head Neck Surg 122(5):775
Vlachou S, Terzakis G, Doundoulakis G, Barbati C, Papazoglou G (2001) Ossifying fibroma of the temporal bone. J Laryngol Otol 115(8):654–656
Ribeiro AC, Carlos R, Diaz KP, Gouvea AF, Vargas PA (2011) Bilateral central ossifying fibroma affecting the mandible: report of an uncommon case and critical review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111:e21–e26
Marx R, Stern D (2003) Oral and maxillofacial pathology. Quintessence, Chicago, pp 789–791
Godt A, Gulicher D, Kalwitzki M, Krober SM (2008) Dislocation of an upper third molar by an ossifying fibroma—Case report. J Craniomaxillofac Surg 36(6):360–364
Voytek TM, Roj Y, Edeiken J (1995) Fibrous dysplasia and cemento ossifying fibroma. A histological spectrum. Am J Surg Pathol 19(7):775–781
Campanacci M (1976) Osteofibrous dysplasia of long bones: a new clinical entity. Ital J Orthop Traumatol 2(2):221–237
Hammer JE, Scofied HH, Cornyn J (1968) Benign fibro-osseous jaw lesions of periodontal membrane origin: an analysis of 249 cases. Cancer 22(4):861–878
Jaff HL, Lichtenstein (1942) Non-osteogenic fibroma of bone. Am J Pathol 18(2):205–221
Pederson CW (1971) Fibro-osseous lesion of the mandible: cementifying fibroma: report of a case. J Oral Surg 29(4):280–284
Bradley ES, Leake D (1968) Ossifying fibroma involving the maxilla and mandible. Oral Surg Oral Med Oral Pathol 26(5):605–614
Kridel RWH, Miller RH, Greenberg SD (1983) Ossifying fibroma: diagnostic classification. Otolaryngol Head Neck Surg 91(5):568–573
Eversole LR, Leider AS, Nelson K (1985) Ossifying fibroma: a clinicopathological study of sixty-four cases. Oral Surg 60(5):505–511
Sciubba JJ, Younai F (1989) Ossifying finroma of the mandible and maxilla: review of 18 cases. J Oral Pathol Med 18(6):315–321
Mintz S, Velez I (2007) Central ossifying fibroma: an analysis of 20 cases and review of literature. Quintessence Int 38(3):221–227
Toyosawa S, Yuki M, Kishino M, Ogawa Y, Ueda T, Murakami S et al (2007) Ossifying fibroma vs fibrous dysplasia of the jaw: molecular and immunological characterization. Mod Pathol 20(3):389–396
Booth PW, Schendel SA, Hausamen JE (2007) Maxillofacial surgery, 2nd edn. Churchill Livingstone. St. Louis, Missouri, pp 506–509
Regezi JA, Sciubba JJ (1999) Oral pathology—clinical pathological correlations, 3rd edn. WB Saunders Co, Philadelphia, pp 357–360
Ong AHM, Siar CH (1998) Cemento-ossifying fibroma with mandibular fracture: case report in a young patient. Austr Dent J 43(4):229–233
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Mohanty, S., Gupta, S., Kumar, P. et al. Retrospective Analysis of Ossifying Fibroma of Jaw Bones Over a Period of 10 Years with Literature Review. J. Maxillofac. Oral Surg. 13, 560–567 (2014). https://doi.org/10.1007/s12663-013-0545-0
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DOI: https://doi.org/10.1007/s12663-013-0545-0