Skip to main content
SpringerLink
Log in

Role of Collagen Impregnated with Dexamethasone and Placentrix in Patients with Oral Submucous Fibrosis

  • Original paper
  • Published:
Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Purpose

To evaluate the versatility of the collagen membrane as both drug carrier and biologic dressing material to cover the raw wounds created after the surgical excision of fibrotic bands in oral submucous fibrosis.

Materials and Methods

The study comprises of ten patients. The patients of age group 20 to 50 years were selected. The collagen is reconstituted by injecting with dexamethasone and placentrix solution leaving a small overlap on to the remaining mucous membrane and the graft is sutured. Preoperative and post operative assessment was done regarding the improvement in mouth opening, decrease in burning sensation, change in colour of oral mucosa and clinically grading the extent of lesion.

Results

The results were found appreciable in seven patients while in the remaining three patients it showed relapse because of inadequate physiotherapy. All the ten patients were comfortable with intra oral collagen grafting. The collagen remained moist and supple intraorally, and remained in close contact with the underlying tissues, providing a strong mechanical barrier. The material was effective in attaining haemostasis, relieving pain and preventing extensive contracture.

Conclusion

In this study of short duration, the nature of collagen membrane was observed as both biological dressing material and drug carrier. It was found as a very suitable alternative to the other graft material mentioned for the repair of defects in the mucous membrane created by surgical excision of fibrous bands in oral submucous fibrosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Cox SC, Walker DM (1996) Oral submucous fibrosis. A review. Aust Dent J 41(5):294–299

    Article  PubMed  CAS  Google Scholar 

  2. Lai DR, Chen HR (1995) Clinical evaluation of different treatment methods for oral submucousfibrosis. A 10-year experience with 150 cases. J Oral Pathol Med 24:402–406

    Article  PubMed  CAS  Google Scholar 

  3. Khanna JN, Andrade NN (1995) Oral submucous fibrosis: a new concept in surgical management. Int J Oral Maxillofacial Surg 24:433–439

    Article  CAS  Google Scholar 

  4. Gupta Dinesh Chandra S, Dolas Rameeshwar S, Iqbal Ali (1992) Treatment modalities in oral submucous fibrosis: how they stand today? study of 600 cases. Ind J Oral Maxillofac Surg 7:43–47

    Google Scholar 

  5. Alexander John M, Richmond JL (1978) Microfibrillar collagen (Avitene) a haemostatic agent in experimental oral wounds. Journal of oral surgery 36:202–205

    PubMed  CAS  Google Scholar 

  6. Rananjaneyulu P, Prabhakara Rao BS (1980) Sub mucous fibrosis—new treatment. J Indian Dent Assoc 52:379–380

    Google Scholar 

  7. Sanjay Rastoji, Mancy Modi, Brijesh Sathian (2009) The efficacy of collagen membrane as biodegradable wound dressing material for surgical defects of oral mucosa: a prospective study. J Oral Maxillofac Surg 67:1600–1606

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Krishnadevaraya College of Dental Sciences, Hunsamarana Halli, Via, Yelhanka, Bangalore, India

    Y. Raghavendra Reddy, N. Srinath & H. Nandakumar

  2. G Pulla Reddy Dental College, Kurnool, Andhra Pradesh, India

    M. Rajini Kanth

Authors
  1. Y. Raghavendra Reddy
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. Srinath
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Nandakumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. Rajini Kanth
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Y. Raghavendra Reddy.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Raghavendra Reddy, Y., Srinath, N., Nandakumar, H. et al. Role of Collagen Impregnated with Dexamethasone and Placentrix in Patients with Oral Submucous Fibrosis. J. Maxillofac. Oral Surg. 11, 166–170 (2012). https://doi.org/10.1007/s12663-011-0274-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12663-011-0274-1

Keywords

Search

Navigation