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Isospora belli associated recurrent diarrhea in a child with AIDS

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Abstract

Persistent diarrhea is a major manifestation of Acquired Immunodeficiency Syndrome (AIDS) which might be more complicated in Human Immunodeficiency Virus (HIV) infected children especially those from developing countries. There are numerous reports showing the emergence of intestinal opportunistic coccidian parasites, mostly Cryptosporidium parvum and Isospora belli in HIV-infected individuals. The prevalence of isosporiasis is probably underestimated in developing countries because routinely not all HIV-infected patients are examined for the presence of this protozoan infection. Here we report a case of HIV-infected isosporiasis presenting with failure to thrive and persistent diarrhea. Since I. belli infection in children responds well to therapy with trimethoprim-sulfamethoxazole, isosporiasis should be considered as a treatable infection in AIDS, if it is detected at proper time.

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References

  • Agholi M, Hatam GR, Motazedian MH (2013) HIV/AIDS-associated opportunistic protozoal diarrhea. AIDS Res Hum Retrovir 29:35–41

    Article  PubMed  PubMed Central  Google Scholar 

  • Arora DR, Arora B (2009) AIDS-associated parasitic diarrhea. Indian J Med Microbiol 27:185–190

    Article  PubMed  CAS  Google Scholar 

  • Behera B, Mirdha BR, Makharia GK et al (2008) Parasites in patients with malabsorption syndrome: a clinical study in children and adults. Dig Dis Sci 53:672–699

    Article  PubMed  Google Scholar 

  • Benator DA, French AL, Beaudet LM, Levy CS, Orenstein JM (1994) Isospora belli infection associated with acalculous cholecystitis in a patient with AIDS. Ann Intern Med 121:663–664

    Article  PubMed  CAS  Google Scholar 

  • Brandborg LL, Goldberg SB, Breidenbach WC (1970) Human coccidiosis-a possible cause of malabsorption. N Engl J Med 283:1306–1313

    Article  PubMed  CAS  Google Scholar 

  • Certad G, Arenas-Pinto A, Pocaterra L et al (2003) Isosporiasis in Venezuelan adults infected with human immunodeficiency virus: clinical characterization. Am J Trop Med Hyg 69:217–222

    PubMed  Google Scholar 

  • Gupta S, Narang S, Nunavath V, Singh S (2008) Chronic diarrhea in HIV patients: prevalence of coccidian parasites. Indian J Med Microbiol 26:172–175

    Article  PubMed  CAS  Google Scholar 

  • Hazrati Tappeh Kh, Mohammad Zadeh H, Mohammedi A, Yousefi MH (2001) A case report of Isospora belli from west Azerbayjan province, Iran. Urmia Med J 12(3) (Persian)

  • Joshi M, Chowdhary AS, Dalal PJ, Maniar JK (2002) Parasitic diarrhea in patients with AIDS. Natl Med J India 15:72–74

    PubMed  Google Scholar 

  • Koru O, Araz RE, Yilmaz YA et al (2007) Case report: Isospora belli infection in a renal transplant recipient. Turkiye Parazitol Derg 31:98–100

    PubMed  Google Scholar 

  • Meamar AR, Rezaian M, Mirzaei AZ et al (2009) Severe diarrhea due to Isospora belli in a patient with thymoma. J Microbiol Immunol Infect 42:526–529

    PubMed  Google Scholar 

  • Mirdha BR, Kabra SK, Samantray JC (2002) Isosporiasis in children. Indian Pediatr 39:941–944

    PubMed  Google Scholar 

  • Resiere D, Vantelon JM, Bourée P et al (2003) Isospora belli infection in a patient with non-Hodgkin’s lymphoma. Clin Microbiol Infect 9:1065–1067

    Article  PubMed  CAS  Google Scholar 

  • Restrepo C, Macher AM, Radany EH (1987) Disseminated extraintestinal isosporiasis in a patient with acquired immune deficiency syndrome. Am J Clin Pathol 87:536–542

    PubMed  CAS  Google Scholar 

  • Thea DM, St Louis ME, Atido U et al (1993) A prospective study of diarrhea and HIV-1 infection among 429 Zairian infants. N Engl J Med 329:1696–1702

    Article  PubMed  CAS  Google Scholar 

  • Vignesh R, Balakrishnan P, Shankar EM et al (2007) Short report: high proportion of isosporiasis among HIV-infected patients with diarrhea in southern India. Am J Trop Med Hyg 77:823–824

    PubMed  CAS  Google Scholar 

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The authors declare that they have no conflicts of interest.

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Correspondence to B. Nikmanesh.

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Nateghi Rostami, M., Nikmanesh, B., Haghi-Ashtiani, M.T. et al. Isospora belli associated recurrent diarrhea in a child with AIDS. J Parasit Dis 38, 444–446 (2014). https://doi.org/10.1007/s12639-013-0272-y

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  • DOI: https://doi.org/10.1007/s12639-013-0272-y

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