Skip to main content

Successful management of refractory cases of canine demodicosis with homeopathy medicine Graphitis


Canine demodicosis is a refractory skin disease caused by excessive proliferation of mite Demodex canis. Despite availability of several treatment options, the disease poses a great challenge to clinicians for its long term management as some drugs may be ineffective or toxic. Present report describes successful treatment of two refractory cases of canine demodicosis using homeopathy medicine. After oral administration of Graphitis 200 C two drops once daily for 2 months, complete cure from the disease was observed. No adverse health effects of the medication were recorded during the treatment. Thus, it may be concluded that homeopathy medicine may be used safely for long-term management of canine demodicosis.

This is a preview of subscription content, access via your institution.

Fig. 1
Fig. 2
Fig. 3


  • Aujla RS, Singla LD, Juyal PD, Gupta PP (2000) Prevalence and pathology of mange-mite infections in dogs. J Vet Parasitol 14:45–49

    Google Scholar 

  • Bettenay S (1998) A double-blind trial evaluating homeopathic drops in the treatment of atopy in 20 dogs. In: Kwochka KW, Willemse T, Von Tscharner C (eds) Advances in veterinary dermatology, vol 3. Butterworth-Heinemann, Boston, pp 508–509

    Google Scholar 

  • Ghubash R (2006) Parasitic miticidal therapy. Clinical Tech Small Anim Pract 21:135–144

    Article  Google Scholar 

  • Gortel K (2006) Update on canine demodicosis. Vet Clinics North Am Small Anim Pract 36:229–241

    Article  Google Scholar 

  • Hill PB, Hoare J, Lau-Gillard P, Rybnicek R, Mathie T (2009) Pilot study of the effect of individual homeopathy on the pruritus associated with atopic dermatitis in dogs. Vet Rec 164:364–370

    PubMed  Article  CAS  Google Scholar 

  • Hugnet C, Buronrosse F, Pineau X, Cadore JL, Lorgue G, Berny PJ (1996) Toxicity and kinetics of amitraz in dogs. Am J Vet Res 57:1506–1510

    PubMed  CAS  Google Scholar 

  • Merola VM, Eubig PA (2012) Toxicology of avermectins and milbemycins (macrocylic lactones) and the role of P-glycoprotein in dogs and cats. Vet Clinics North Am Small Anim Pract 42:313–333

    Article  Google Scholar 

  • Muller RS (2004) Treatment protocols for demodicosis: an evidence-based review. Vet Dermatol 15:75–89

    Article  Google Scholar 

  • Paradis M (1999) New approaches to the treatment of canine demodicosis. Vet Clin North Am Small Anim Pract 29:1425–1436

    PubMed  CAS  Google Scholar 

  • Scott DW, William H, Miller Jr, Senter DA, Cook CP, Kirker JE, Shaun MC (2002) Treatment of canine atopic dermatitis with a commercial homeopathic remedy: a single-blinded, placebo-controlled study. Can Vet J 43:601–603

    PubMed  PubMed Central  Google Scholar 

  • Sood NK, Mekkib B, Singla LD, Gupta K (2012) Cytopathology of parasitic dermatitis in dogs. J Parasit Dis 36:73–77

    PubMed  Article  CAS  PubMed Central  Google Scholar 

  • Tarallo VD, Lia RP, Sasanelli M, Cafarchia C, Otranto D (2009) Efficacy of amitraz plus metaflumizone for the treatment of canine demodicosis associated with Malassezia pacydermatitis. Parasit Vectors 2:13. doi:10.1186/1756-3305-2-13

    PubMed  Article  PubMed Central  Google Scholar 

  • Urquhart GM (1996) Veterinary parasitology. 2nd edn. Blackwell Publishing, ISBN 0-632-04051-3

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Rakesh Ranjan.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Ranjan, R., Dua, K., Turkar, S. et al. Successful management of refractory cases of canine demodicosis with homeopathy medicine Graphitis. J Parasit Dis 38, 417–419 (2014).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI:


  • Canine
  • Demodicosis
  • Graphitis
  • Homeopathy
  • Mange