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Influence of Micro- and Nanoporous Silicon Layers with Different Depth and Pore Morphology on Contact Angle, Adhesion and Viability of Cells

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Abstract

The use of structured silicon substrates as model scaffolds is promising for the systematic study of the role of micro/nanomorphology in cell adhesion and growth. In this study we created nano- and microstructured porous layers on silicon plates using electrochemical etching. Then we investigated the effect of pore depth and size on silicon plate’s contact angle, cell adhesion, and viability. We found that different porosity promotes different cell adhesion. Cells adhere more strongly to plates in the case of nanopores and weaker to micropores. Nanoporous layers were much more hydrophilic compared to the microporous ones.

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Data Availability

Data are available on request from the corresponding author.

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Funding

This work was funded by the Ministry of Science and Higher Education of the Russian Federation under the strategic academic leadership program “Priority 2030”.

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Authors and Affiliations

  1. National University of Science and Technology “MISIS”, 119049, Leninskiy pr. 4, Moscow, Russian Federation

    Artem Iliasov & Ekaterina Gosteva

  2. Institute of Microelectronics Technology and High Purity Materials, Russian Academy of Sciences, 142432, Ossipyan Str., Chernogolovka, Russian Federation

    Vitaly Starkov

Authors
  1. Artem Iliasov
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  2. Vitaly Starkov
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  3. Ekaterina Gosteva
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Contributions

Artem Iliasov: Investigation, Data curation, Writing – original draft, Methodology, Visualization, Funding acquisition. Vitaly Starkov: Investigation, Supervision, Project administration, Writing – review & editing. Ekaterina Gosteva: Conceptualization, Methodology, Validation, Resources, Supervision.

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Correspondence to Artem Iliasov.

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Iliasov, A., Starkov, V. & Gosteva, E. Influence of Micro- and Nanoporous Silicon Layers with Different Depth and Pore Morphology on Contact Angle, Adhesion and Viability of Cells. Silicon 15, 3877–3881 (2023). https://doi.org/10.1007/s12633-023-02300-1

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  • DOI: https://doi.org/10.1007/s12633-023-02300-1

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