Literatur
Mornet E, Yvard A, Taillandier A et al (2011) A molecular-based estimation of the prevalence of hypophosphatasia in the European population. Ann Hum Genet 75:439-445
Mornet E (2007) The tissue nonspecific alkaline phosphatase gene mutations database. http://www.sesep.uvsq.fr/Database.html. Zugegriffen 02. Nov. 2020
Rathbun JC (1948) Hypophosphatasia; a new developmental anomaly. Am J Dis Child 75:822-831
Sobel EH, Clark LC, Fox RP et al (1953) Rickets, deficiency of alkaline phosphatase activity and premature loss of teeth in childhood. Pediatrics 11:309-322
Salles JP (2020) Hypophosphatasia: biological and clinical aspects, avenues for therapy. Clin Biochem Rev 41:13-27
Okawa R, Nakano K, Matsumoto M et al (2012) Oral manifestations of patients with hypophosphatasia. Pediatr Dent J 22:155-162
Hennings R, Roth A, Seefried L (2015) Hypophosphatasie. In: Osteologie, S 200-207
Hollis A, Arundel P, High A, Balmer R (2013) Current concepts in hypophosphatasia: case report and literature review. Int J Paediatr Dent 23:153-159
Whyte MP, Leung E, Wilcox WR et al (2019) Natural history of perinatal and infantile hypophosphatasia: a retrospective study. J Pediatr 209:116-124.e4
Högler W, Langman C, Gomes da Silva H et al (2019) Diagnostic delay is common among patients with hypophosphatasia: initial findings from a longitudinal, prospective, global registry. BMC Musculoskelet Disord 20:80
Seefried L, Baumann J, Hemsley S et al (2017) Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia. J Clin Invest 127:2148-2158
Hofmann C, Seefried L, Jakob F (2016) Asfotase alfa: enzyme replacement for the treatment of bone disease in hypophosphatasia. Drugs Today (Barc) 52:271-285
Whyte MP, Greenberg CR, Salman NJ et al (2012) Enzyme-replacement therapy in life-threatening hypophosphatasia. N Engl J Med 366:904-913
Whyte MP, Madson KL, Phillips D et al (2016) Asfotase alfa therapy for children with hypophosphatasia. JCI Insight. DOI 10.1172/jci.insight.85971
Whyte MP, Rockman-Greenberg C, Ozono K et al (2016) Asfotase alfa treatment improves survival for perinatal and infantile hypophosphatasia. J Clin Endocrinol Metab 101:334-342
McKee MD, Nakano Y, Masica DL et al (2011) Enzyme replacement therapy prevents dental defects in a model of hypophosphatasia. J Dent Res 90:470-476
Schilke R, Schlagenhauf U (2018) Odontohypophosphatasie. Thieme-Refresher Zahnheilkd 10:1-16
Hofmann C, Girschick HJ, Mentrup B et al (2013) Clinical aspects of hypophosphatasia: an update. Clin Rev Bone Miner Metab11:60-70
Harks I, Koch R, Eickholz P et al (2015) Is progression of periodontitis relevantly influenced by systemic antibiotics? A clinical randomized trial. J Clin Periodontol 42:832-842
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Heß, J., Stölzel, P. Hypophosphatasie. DFZ 65, 52–57 (2021). https://doi.org/10.1007/s12614-020-9479-3
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12614-020-9479-3