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Relations entre fragilité et nutrition chez le sujet âgé

Relationship between frailty and nutrition in the elderly

  • Article Original / Original Article
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Les cahiers de l'année gérontologique

Résumé

De par ses conséquences et sa prévalence élevée, la fragilité peut être considérée comme un problème majeur chez le sujet âgé. Son origine est multifactorielle, compte tenu de la fréquence des déficits nutritionnels, leurs rôles quant à la survenue de la fragilité doivent être connus. Il est désormais bien établi que des apports protéiques et énergétiques insuffisants sont directement reliés à la fragilité par l’intermédiaire de plusieurs de ses composantes. Les données récentes soulignent aussi toute l’importance des micronutriments dont le déficit conduit à une fragilité indépendamment du rôle des macronutriments. Les données disponibles indiquent que les aspects qualitatifs doivent aussi être pris en compte dans l’alimentation des personnes âgées. Un suivi tenant compte de ces différents aspects apparaît un élément majeur dans la stratégie de prévention et de prise en charge de la fragilité.

Abstract

Due to the consequences and its increased prevalence, frailty can be considered as a common problem for the elderly patient, with its origins linked to a number of factors; the frequency of poor nutrition and its role in causing frailty needs to be understood. It is, however, well established that insufficient protein intake and a lack of exercise are directly related to frailty, due to a combination of many components. Recent data also highlights the importance of micronutrients, a lack of which can lead to frailty, independent of the role of macronutrients. This data indicates that qualitative aspects must also be taken into consideration when it comes to providing food for the elderly. Careful monitoring of these different aspects would appear to be a key factor in prevention strategies and the management of frailty.

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Références

  1. Fried L, Tangen CM, Walston J, et al (2001) Frailty in older adults: evidence for a phenotype. J Gerontol 56(3):M146–M156

    CAS  Google Scholar 

  2. Houston DK, Nicklas BJ, Ding J, et al (2008) Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr 87:150–155

    PubMed  CAS  Google Scholar 

  3. BrodskyI G, Suzara D, Hornberger TA, et al (2004) Isoenergetic dietary protein restriction decreases myosin heavy chain IIx fraction and myosin heavy chain production in humans. J Nutr 134:328–334

    Google Scholar 

  4. Beasley JM, LaCroix AZ, Neuhouser ML, et al (2010) Protein intake and incident frailty in the women’s health initiative observational study. JAGS 58:1063–1071

    Article  Google Scholar 

  5. Milne AC, Avenell A, Potter J (2006) Meta-analysis: protein and energy supplementation in older people. Ann Intern Med 144:37–48

    PubMed  CAS  Google Scholar 

  6. Campbell WW, Trappe TA, Wolfe RR, Evans WJ (2001) The recommended dietary allowance for protein may not be adequate for older people to maintain skeletal muscle. J Gerontol A Biol Sci Med Sci 56A:M373–M380

    Article  CAS  Google Scholar 

  7. Volpi E, Kobayashi H, Sheffield-Moore M, et al (2003) Essential amino-acids are primarily responsible for the amino-acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr 78:250–258

    PubMed  CAS  Google Scholar 

  8. Dardevet D, Sornet C, Balage M, et al (2000) Stimulation of in vitro rat muscle protein synthesis by leucine decreases with age. J Nutr 130(11):2630–2635

    PubMed  CAS  Google Scholar 

  9. Lord C, Chaput JP, Aubertin-Leheudre M, et al (2007) Dietary animal protein intake: association with muscle mass index in older women. J Nutr Health Aging 11:383–387

    PubMed  CAS  Google Scholar 

  10. Campbell WW, Leidy HJ (2007) Dietary protein and resistance training effects on muscle and body composition in older persons. J Am Coll Nutr 26(6):696–703

    Google Scholar 

  11. Bartali B, Frongillo EA, Bandinelli S, et al (2006) Low nutrient intake is an essential component of frailty in older persons. J Gerontol A Biol Sci Med Sci 61(6):5895–5993

    Article  Google Scholar 

  12. Gaillard C, Alix E, Sallé A, et al (2007) Energy requirements in frail elderly people: a review of the literature. Clin Nutr 26 (1):16–24

    Article  PubMed  CAS  Google Scholar 

  13. Vellas BJ, Hunt WC, Romero LJ, et al (1997) Changes in nutritional status and patterns of morbidity among free-living elderly persons: a 10-year longitudinal study. Nutrition 13(6):515–519

    Article  PubMed  CAS  Google Scholar 

  14. Michelon E, Blaum C, Semba RD, et al (2006) Vitamin and carotenoid status in older women: associations with the frailty syndrome. J Gerontol A Biol Sci Med Sci 61A(6):600–607

    Article  CAS  Google Scholar 

  15. Semba RD, Bartali B, Zhou J, et al (2006) Low serum micronutrient concentrations predict frailty among older women living in the community. J Gerontol A Biol Sci Med Sci 61A:594–599

    Article  CAS  Google Scholar 

  16. Food and Nutrition Board, Institute of Medicine (2000) Dietary Reference intakes for vitamin C, vitamin E, selenium, and carotenoids. National Academy Press, Washington DC

    Google Scholar 

  17. Lopez-Garcia E, Schulze MB, Fung TT, et al (2004) Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr 80:1029–1035

    PubMed  CAS  Google Scholar 

  18. Kim JS, Wilson JM, Lee SR (2010) Dietary implications on mechanisms of sarcopenia: roles of protein, amino-acids and antioxidants. J Nutr Biochem 21:1–13

    Article  PubMed  Google Scholar 

  19. Dirks A, Leenwenburgh C (2002) Apoptosis in skeletal muscle with aging. Am J Physiol Regul Integr Comp Physiol 282:519–527

    Google Scholar 

  20. Marzani B, Balage M, Vénien A, et al (2008) Antioxidant supplementation restores defective leucine stimulation of protein synthesis in skeletal muscle from old rats. J Nutr 138:2205–2211

    Article  PubMed  CAS  Google Scholar 

  21. Milaneschi Y, Bandinelli S, Corsi AM, et al (2011) Mediterranean diet and mobility decline in older persons. Exp Gerontol 46:303–308

    Article  PubMed  Google Scholar 

  22. Bobeuf F, Labonte M, Dionne IJ, Khalil A (2011) Combined effect of antioxidant supplementation and resistance training on oxidative stress markers, muscle and body composition in an elderly population. J Nutr Health Aging 15(10):883–889

    Article  PubMed  CAS  Google Scholar 

  23. Yetley EA (2008) Assessing the vitamin D status of the US population. Am J Clin Nutr 88:558–564

    Google Scholar 

  24. Hirani V, Primatesta P (2005) Vitamin D concentrations among people aged 65 years and over living in private households and institutions in England: population survey. Age Ageing 34:485–491

    Article  PubMed  Google Scholar 

  25. Wilhelm-Leen ER, Hall YN, deBoer IH, Chertow GM (2010) Vitamin D deficiency and frailty in older Americans. J Intern Med 268(2):171–180

    Article  PubMed  CAS  Google Scholar 

  26. Ensrud KE, Ewing SK, Fredman L, et al (2010) Circulating 25-hydroxyvitamin D levels and frailty status in older women. J Clin Endocrinol Metab 95(12):5266–5273

    Article  PubMed  CAS  Google Scholar 

  27. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, et al (2009) Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. BMJ 339:b3692

    Article  PubMed  CAS  Google Scholar 

  28. Dawson-Hughes B (2011) Serum 25-hydroxyvitamin D and muscle atrophy in the elderly. Proc Nutr Soc 1:1–4

    Google Scholar 

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Authors and Affiliations

  1. Service de médecine gériatrique, groupement hospitalier Sud, Hospices civils de lyon, Inserm 1060, université Claude-Bernard-Lyon-I, F-69495, Pierre-Bénite cedex, France

    M. Bonnefoy

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Bonnefoy, M. Relations entre fragilité et nutrition chez le sujet âgé. cah. année gerontol. 4, 9–12 (2012). https://doi.org/10.1007/s12612-012-0256-z

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  • DOI: https://doi.org/10.1007/s12612-012-0256-z

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