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Stress périnatal et développement neuropsychologique

Perinatal stress and neuropsychological development

  • Article De Synthèse / Review Article
  • Published:
Revue de médecine périnatale

Résumé

Depuis deux décennies, la recherche expérimentale s’est efforcée de modéliser le stress périnatal et ses conséquences cliniques et biologiques. En laboratoire, l’effet du stress s’apparente à celui d’une programmation développementale et peut rendre compte de la survenue ultérieure de pathologies neuropsychologiques. Si un tel niveau de preuve n’est pas établi en clinique humaine, plusieurs observations suggèrent l’intervention modulatrice du stress périnatal dans le développement à court et long terme de l’enfant, ainsi qu’une vulnérabilité accrue aux troubles psychopathologiques. Après avoir rappelé les principaux modèles, cette revue présente quelques stratégies cliniques intégrant la gestion du stress dans l’objectif d’en limiter le retentissement.

Abstract

Over the past 20 years, experimental researchers have attempted to experimentally model perinatal stress in order to determine its clinical and biological consequences. In the laboratory, the effect of stress appears similar to that of developmental programming and could account for the subsequent occurrence of neuropsychological pathologies. Although this level of proof has not been clinically established, several observations suggest that perinatal stress has a modulating effect on the infant’s short- and long-term development, with an increased vulnerability for psychiatric disorders. This review considers the principal models and then presents some of the clinical strategies that integrate stress management in order to limit its repercussions.

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Author information

Authors and Affiliations

  1. Service de pédiatrie néonatale et de réanimations, département de pédiatrie, pôle Enfant, hôpital Arnaud-de-Villeneuve, CHU de Montpellier, 371, avenue du Doyen-G. Giraud, F-34295, Montpellier cedex 5, France

    G. Cambonie, A. Rideau, M. Bienfait & O. Pidoux

  2. Laboratoire stress oxydant et neuroprotection, université de Montpellier-II, institut Max-Mousseron des biomolécules de Montpellier, bâtiment 24, 3e étage, place Eugène-Bataillon-cc 2400, F-34095, Montpellier cedex 5, France

    G. Cambonie, A. Rideau & G. Barbanel

  3. Médecine psychologique pour enfants et adolescents, clinique Peyre-Plantade, CHU de Montpellier, Montpellier, France

    R.-M. Toubin

  4. Service de néonatologie, hôpital de la Croix-Rousse, CHU de Lyon, Lyon, France

    J.-C. Picaud

Authors
  1. G. Cambonie
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  2. A. Rideau
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  3. M. Bienfait
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  4. O. Pidoux
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  5. R.-M. Toubin
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  6. J.-C. Picaud
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  7. G. Barbanel
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Corresponding author

Correspondence to G. Cambonie.

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Cambonie, G., Rideau, A., Bienfait, M. et al. Stress périnatal et développement neuropsychologique. Rev. med. perinat. 2, 122–130 (2010). https://doi.org/10.1007/s12611-010-0072-x

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  • DOI: https://doi.org/10.1007/s12611-010-0072-x

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