Effect of Body Weight, Waist Circumference and their Changes on Mortality: A 10-Year Population-Based Study

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Abstract

Objectives

To investigate the effect of body weight, waist circumference and their changes on all-cause and cardiovascular mortality.

Design

A nationwide population-based cohort study

Participants

627 community-dwelling older adults.

Measurements

Participants were interviewed for demographic and anthropometric data collected. Blood were drawn for testing biochemistry data. Central obesity was defined as waist circumference is greater than 80 cm for women and 90 cm for men. Obesity, overweight, normal and underweight were defined as BMI ≥27 kg/m2, ≥24 kg/m2,18.5-24 kg/m2 and <18.5 kg/m2. Cox proportion hazard model was used to explore the impact of body weight and its change on mortality.

Results

The distribution of weight changes and mortality was right skewed, but U-shape of waist change for all-cause mortality was observed. Compared to normal BMI at baseline, the association between underweight (HR: 1.7, 95% CI: 0.7-4.0), overweight (HR:0.7, 95% CI:0.4-1.2) and obesity (HR:1.3,95% CI:0.8-2.3) showed insignificantly associated with all-cause mortality. The HR of those weight loss >5% (HR: 1.7, 95% CI: 1.1-2.8) and waist decrease >5% (HR: 1.7, 95% CI: 1.0-2.8) were higher than those of stable weight/waist +/- 5% over a 6-year period. Compared to those stable weight/waist, the mortality risk was similar in those of weight gain or waist increase (HR 0.7,95%CI: 0.4-1.5 and HR:0.9, 95%CI:0.4-1.6).

Conclusion

Weight loss and waist decrease were significantly associated with long-term mortality risk, a life-course approach for body weight management is needed to pursuit the most optimal health benefits for the middle-aged and older adults.

Key words

Body weight index body weight change mortality population-based study 

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Copyright information

© Serdi and Springer-Verlag France SAS, part of Springer Nature 2018

Authors and Affiliations

  • W.-J. Lee
    • 1
    • 2
    • 3
  • L.-N. Peng
    • 1
    • 2
    • 4
  • C.-H. Loh
    • 1
    • 2
    • 5
  • Liang-Kung Chen
    • 1
    • 2
    • 4
  1. 1.Aging and Health Research CenterNational Yang Ming UniversityTaipeiTaiwan
  2. 2.Department of GeriatricsNational Yang Ming University School of MedicineTaipeiTaiwan
  3. 3.Department of Family MedicineTaipei Veterans General Hospital Yuanshan BranchYi-LandTaiwan
  4. 4.Center for Geriatrics and GerontologyTaipei Veterans General HospitalTaipeiTaiwan
  5. 5.Center of Health and Aging,Hualien Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationHualienTaiwan

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