Decline and Peripheral Redistribution of Fat Mass in Old Age - A Four-Year Prospective Study in 3018 Older Community-Living Adults

  • T. W. AuYeung
  • J. Leung
  • R. Yu
  • J. S. W. Lee
  • T. Kwok
  • J. Woo
Article
  • 13 Downloads

Abstract

Background

It is widely recognized that fat will accumulate with ageing and is more prominent centrally. However, there were studies reported that fat might not gain either centrally or generally with ageing.

Methods

The baseline, 2-year and 4-year total body fat mas, trunk fat mass and percentage fat mass, were measured by DXA in 3018 community-living Chinese older than 65 years. The respective 4-year trajectories of adiposity were analyzed by repeated measure ANOVA p-for-trend test.

Results

There was a trend of increase in total body fat mass in men and a decreasing trend in women but neither reached statistical significance. However, there was a significant increase in percent fat mass in both genders. Fat mass was relatively stable in the 2 youngold groups but it declined in the oldest group, aged 75 years or above. (men, p=0.017; women, p<0.001). On the contrary, a corresponding rise of percent fat mass was observed, which was steeper in the 2 younger age groups but did not change in the oldest group. For trunk fat mass, there was a statistically significant decreasing trend in women (p < 0.001) but it remained static in men (p = 0.092). The fat mass in upper limbs of both genders did not change but for the lower limbs, there was a statistically significant increase in both men (p < 0.001) and women (p < 0.02).

Conclusions

Absolute total body fat mass does not accumulate in old age and in the contrary, in the oldest old group (75 years or above), it declined instead. With ageing, fat will redistribute from the central region to the lower limbs.

Key words

Fat mass prospective elderly 

References

  1. 1.
    Hughes VA, Frontera WR, Roubenoff R, Evans WJ, Singh MA. Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. The American journal of clinical nutrition. 2002 Aug 1;76(2):473–81.CrossRefPubMedGoogle Scholar
  2. 2.
    Visser M, Pahor M, Tylavsky F, Kritchevsky SB, Cauley JA, Newman AB, Blunt BA, Harris TB. One-and two-year change in body composition as measured by DXA in a population-based cohort of older men and women. Journal of applied physiology. 2003 Jun 1;94(6):2368–74.CrossRefPubMedGoogle Scholar
  3. 3.
    Hughes VA, Roubenoff R, Wood M, Frontera WR, Evans WJ, Singh MA. Anthropometric assessment of 10-y changes in body composition in the elderly. The American journal of clinical nutrition. 2004 Aug 1;80(2):475–82.CrossRefPubMedGoogle Scholar
  4. 4.
    Jackson AS, Janssen I, Sui X, Church TS, Blair SN. Longitudinal changes in body composition associated with healthy ageing: men, aged 20–96 years. British Journal of Nutrition. 2012 Apr;107(7):1085–91.CrossRefPubMedGoogle Scholar
  5. 5.
    Bazzocchi A, Diano D, Ponti F, Andreone A, Sassi C, Albisinni U, Marchesini G, Battista G. Health and ageing: a cross-sectional study of body composition. Clinical nutrition. 2013 Aug 31;32(4):569–78.CrossRefPubMedGoogle Scholar
  6. 6.
    Shimokata H, Tobin JD, Muller DC, Elahi D, Coon PJ, Andres R. Studies in the distribution of body fat: I. Effects of age, sex, and obesity. Journal of gerontology. 1989 Mar 1;44(2):M66–73.PubMedGoogle Scholar
  7. 7.
    Schwartz RS, Shuman WP, Bradbury VL, Cain KC, Fellingham GW, Beard JC, Kahn SE, Stratton JR, Cerqueira MD, Abrass IB. Body fat distribution in healthy young and older men. Journal of Gerontology. 1990 Nov 1;45(6):M181–5.CrossRefPubMedGoogle Scholar
  8. 8.
    Kuk JL, Saunders TJ, Davidson LE, Ross R. Age-related changes in total and regional fat distribution. Ageing research reviews. 2009 Oct 31;8(4):339–48.CrossRefPubMedGoogle Scholar
  9. 9.
    Steen B. Body composition and aging. Nutrition Reviews. 1988 Feb 1;46(2):45–51.CrossRefPubMedGoogle Scholar
  10. 10.
    Baumgartner RN, Stauber PM, McHugh D, Koehler KM, Garry PJ. Cross-sectional age differences in body composition in persons 60+ years of age. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 1995 Nov 1;50(6):M307–16.CrossRefGoogle Scholar
  11. 11.
    Silver AJ, Guillen CP, Kahl MJ, Morley JE. Effect of aging on body fat. Journal of the American Geriatrics Society. 1993 Mar 1;41(3):211–3.CrossRefPubMedGoogle Scholar
  12. 12.
    Buffa R, Floris GU, Putzu PF, Marini E. Body composition variations in ageing. Collegium antropologicum. 2011 Mar 7;35(1):259–65.PubMedGoogle Scholar
  13. 13.
    Hughes VA, Roubenoff R, Wood M, Frontera WR, Evans WJ, Singh MA. Anthropometric assessment of 10-y changes in body composition in the elderly. The American journal of clinical nutrition. 2004 Aug 1;80(2):475–82.CrossRefPubMedGoogle Scholar
  14. 14.
    Ding J, Kritchevsky SB, Newman AB, Taaffe DR, Nicklas BJ, Visser M, Lee JS, Nevitt M, Tylavsky FA, Rubin SM, Pahor M. Effects of birth cohort and age on body composition in a sample of community-based elderly. The American journal of clinical nutrition. 2007 Feb1;85(2):405–10.CrossRefPubMedGoogle Scholar
  15. 15.
    Zaslavsky O, Rillamas-Sun E, Li W, Going S, Datta M, Snetselaar L, Zelber-Sagi S. Association of dynamics in lean and fat mass measures with mortality in frail older women. The journal of nutrition, health & aging. 2017 Jan 1;21(1):112–9.CrossRefGoogle Scholar
  16. 16.
    Prior BM, Cureton KJ, Modlesky CM, Evans EM, Sloniger MA, Saunders M, Lewis RD. In vivo validation of whole body composition estimates from dual-energy X-ray absorptiometry. Journal of applied physiology. 1997 Aug 1;83(2):623–30.CrossRefPubMedGoogle Scholar
  17. 17.
    Albanese CV, Diessel E, Genant HK. Clinical applications of body composition measurements using DXA. Journal of Clinical Densitometry. 2003 Jun 1;6(2):75–85.CrossRefPubMedGoogle Scholar
  18. 18.
    Kelly TL, Wilson KE, Heymsfield SB. Dual energy X-Ray absorptiometry body composition reference values from NHANES. PloS one. 2009 Sep 15;4(9):e7038.CrossRefPubMedPubMedCentralGoogle Scholar
  19. 19.
    Woo J, Yu R, You F. Fitness, fatness and survival in elderly populations. Age (Dordr) 2013;35(3):973–984CrossRefGoogle Scholar
  20. 20.
    Douchi T, Yamamoto S, Yoshimitsu N, Andoh T, Matsuo T, Nagata Y. Relative contribution of aging and menopause to changes in lean and fat mass in segmental regions. Maturitas. 2002 Aug 30;42(4):301–6.CrossRefPubMedGoogle Scholar
  21. 21.
    Deurenberg P, Deurenberg-Yap M, Guricci S. Asians are different from Caucasians and from each other in their body mass index/body fat per cent relationship. Obesity reviews. 2002 Aug 1;3(3):141–6.CrossRefPubMedGoogle Scholar
  22. 22.
    Lear SA, Humphries KH, Kohli S, Birmingham CL. The use of BMI and waist circumference as surrogates of body fat differs by ethnicity. Obesity. 2007 Nov 1;15(11):2817–24.CrossRefPubMedGoogle Scholar

Copyright information

© Serdi and Springer-Verlag France SAS, part of Springer Nature 2018

Authors and Affiliations

  • T. W. AuYeung
    • 1
  • J. Leung
    • 1
  • R. Yu
    • 1
  • J. S. W. Lee
    • 1
  • T. Kwok
    • 1
  • J. Woo
    • 1
  1. 1.Chinese University of Hong KongHong KongChina

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