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A review of the effects of dietary silicon intake on bone homeostasis and regeneration

The journal of nutrition, health & aging volume 18, pages 820–826 (2014)Cite this article

Abstract

Objective

Increasing evidences suggest that dietary Silicon (Si) intake, is positively correlated with bone homeostasis and regeneration, representing a potential and valid support for the prevention and improvement of bone diseases, like osteoporosis. This review, aims to provide the state of art of the studies performed until today, in order to investigate and clarify the beneficial properties and effects of silicates, on bone metabolism.

Methods

We conducted a systematic literature search up to March 2013, using two medical databases (Pubmed and the Cochrane Library), to review the studies about Si consumption and bone metabolism.

Results

We found 45 articles, but 38 were specifically focused on Si studies.

Conclusion

Results showed a positive relationship between dietary Si intake and bone regeneration.

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Authors and Affiliations

  1. Section of Anatomy and Physiopathology, Department of Clinical and Experimental Sciences, University of Brescia, V.le Europa 11, 25123, Brescia, Italy

    Luigi Fabrizio Rodella, V. Bonazza, M. Labanca, C. Lonati & R. Rezzani

Authors
  1. Luigi Fabrizio Rodella
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  2. V. Bonazza
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  3. M. Labanca
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  4. C. Lonati
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  5. R. Rezzani
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Correspondence to Luigi Fabrizio Rodella.

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Rodella, L.F., Bonazza, V., Labanca, M. et al. A review of the effects of dietary silicon intake on bone homeostasis and regeneration. J Nutr Health Aging 18, 820–826 (2014). https://doi.org/10.1007/s12603-014-0555-8

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  • DOI: https://doi.org/10.1007/s12603-014-0555-8

Key words

  • Dietary silicon intake
  • ortho-silicic acid
  • bone regeneration
  • osteoporosis
  • silica scaffolds