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Prevotella copri Improves Selenium Deposition and Meat Quality in the longissimus dorsi Muscle of Fattening Pigs

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Abstract

Selenium is among the important trace elements that influence the quality of meat. Although it has been established that the gut microbiota is closely associated with selenium metabolism, it has yet to be determined whether these microbes influence the accumulation of selenium in muscles. To identify gut microbiota that potentially influence the deposition of selenium in muscles, we compared the colonic microbial composition of pigs characterized by high and low contents of selenium in the longissimus dorsi muscle and accordingly detected a higher abundance of the bacterium Prevotella copri (P. copri) in pigs with a higher muscle selenium content. To verify the effect of P. copri, 16 pigs weighing approximately 61 kg were fed either a basal diet or a basal diet supplemented with P. copri (1.0 × 1010 CFU/kg feed) for 45 days. The results revealed significant increases in the contents of selenium and selenoprotein in the serum and longissimus dorsi muscle of fattening pigs fed the P. copri–supplemented diet. Moreover, supplementing the feed of pigs with P. copri was observed to promote significant improvement in the antioxidant capacity and quality of meat, including drip loss, pH, and meat color. In conclusion, our findings in this study indicate that P. copri has potential utility as a dietary supplement for improving the selenium status and meat quality in fattening pigs.

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Data Availability

The 16S rRNA sequence data were deposited in the NCBI SRA database (https://www.ncbi.nlm.nih.gov/sra/) under accession number PRJNA1054783.

Abbreviations

LD:

Longissimus dorsi

SelP:

Selenoprotein P

P. copri :

Prevotella copri

BW:

Body weight

IMF:

Intramuscular fat content

HSE:

High selenium group

LSE:

Low selenium group

FBW:

Final body weight

ADG:

Average daily weight gain

ADFI:

Average daily feed intake

GPX:

Glutathione peroxidase

T-AOC:

Total antioxidant capacity

SOD:

Superoxide dismutase

MDA:

Malondialdehyde

OxyMb:

Oxymyoglobin

MetMb:

Methemoglobin

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Acknowledgements

We would like to thank Editage (www.editage.cn) for English language editing.

Funding

This work was supported by the Science and Technology Innovation Program of Hunan Province (2023RC1074), China Agriculture Research System of MOF and MARA (CARS-35), and National Key Research and Development Program of China (2023YFD1301305).

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  1. Jing Liang, Yan Zeng, and Hong Hu contributed equally to this work.

Authors and Affiliations

  1. Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture the Chinese Academy of Sciences, Changsha, 410125, China

    Jing Liang, Yan Zeng, Yulong Yin & Xihong Zhou

  2. College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, 101408, China

    Jing Liang, Yan Zeng, Yulong Yin & Xihong Zhou

  3. College of Animal Science and Technology, Hunan Agricultural University, Changsha, 410128, China

    Hong Hu

  4. Hunan Provincial Key Laboratory of the Traditional Chinese Medicine Agricultural Biogenomics, Changsha Medical University, Changsha, 410208, China

    Xihong Zhou

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Contributions

Jing Liang: Conceptualization, Writing- Original draft preparation, prepared Figs. 1,2 and graph abstract Yan Zeng: Data curation, Writing- Original draft preparation, prepared Figs. 3,4 Hong Hu: Writing- Reviewing and Editing, Resources,prepared Figs. 5,6 and Table 1 Xihong Zhou: Supervision, Project administration, funding Yulong Yin: Supervision.

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Liang, J., Zeng, Y., Hu, H. et al. Prevotella copri Improves Selenium Deposition and Meat Quality in the longissimus dorsi Muscle of Fattening Pigs. Probiotics & Antimicro. Prot. (2024). https://doi.org/10.1007/s12602-024-10340-1

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