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Table 2 Serum biochemical changes of diabetic study groups and high-fat diet study groups

From: Lactobacillus fermentum MCC2759 and MCC2760 Alleviate Inflammation and Intestinal Function in High-Fat Diet-Fed and Streptozotocin-Induced Diabetic Rats

Parameters Baseline levels NC Groups1
High-fat diet-fed study 1 Diabetic study 2
HFDC HFD + MCC2759 HFD + MCC2760 DC D + MCC2759 D + MCC2760
LDL (mg/dL) 94.67 ± 0.39 94.87 ± 0.05a 163.17 ± 10.50d 154.43 ± 0.62c 136.19 ± 10.50b 157.63 ± 7.09c 117.37 ± 1.16b 117.04 ± 1.46b
HDL (mg/dL) 54.01 ± 0.18 53.46 ± 1.34a 48.63 ± 3.45a 50.42 ± 3.69b 52.52 ± 7.44b 50.77 ± 6.09a 61.51 ± 3.18b 68.04 ± 8.37c
Cholesterol (mg/dL) 62.22 ± 0.22 63.57 ± 9.23a 126.75 ± 1.69 d 84.31 ± 2.19c 60.62 ± 3.23a 90.80 ± 8.99b 89.34 ± 2.75b 64.53 ± 8.99a
Triglycerides (mg/dL) 79.95 ± 0.20 79.38 ± 2.73b 139.93 ± 10.91d 81.44 ± 0.77c 54.65 ± 8.11a 143.32 ± 2.7d 90.18 ± 3.00c 68.46 ± 7.63a
Total Protein (g/dL) 7.13 ± 0.11 6.26 ± 1.06c 7.81 ± 0.18c 8.95 ± 0.79d 4.78 ± 0.22a 5.95 ± 0.13a 6.17 ± 0.90b 6.84 ± 1.29d
Uric acid (mg/dL) 4.18 ± 0.36 3.64 ± 0.57a 2.56 ± 0.19b 2.48 ± 1.00a 3.18 ± 0.94c 7.34 ± 3.80b 8.88 ± 6.41d 8.39 ± 1.55c
Urea (mg/dL) 25.38 ± 0.11 24.89 ± 8.40a 10.96 ± 1.01b 10.38 ± 2.34a 11.18 ± 0.42c 52.05 ± 1.16c 40.34 ± 7.47b 36.20 ± 7.70b
Creatinine (mg/dL) 0.84 ± 0.05 0.61 ± 1.85a 0.55 ± 0.008b 0.50 ± 0.04a 0.56 ± 0.02b 1.11 ± 0.05d 0.75 ± 0.01b 1.18 ± 0.10c
Glucose (mg/dL) 119.60 ± 0.31 121.27 ± 8.30a 160.13 ± 13.51c 109.05 ± 6.73a 105.49 ± 5.49a 436.10 ± 5.88d 367.71 ± 2.42c 201.72 ± 5.21b
Albumin (g/dL) 4.39 ± 0.18 3.89 ± 0.71c 2.40 ± 0.33a 3.66 ± 0.37c 3.07 ± 0.58b 3.44 ± 0.45a 3.52 ± 0.12b 3.51 ± 0.21b
SGPT (U/L) 38.83 ± 0.17 39.59 ± 0.02c 26.95 ± 0.36b 20.88 ± 2.40a 21.23 ± 3.08a 18.31 ± 4.19a 28.79 ± 7.15b 41.17 ± 1.07d
SGOT (U/L) 46.05 ± 0.23 45.56 ± 0.03b 42.39 ± 3.06b 29.68 ± 0.61a 42.75 ± 3.57b 45.02 ± 0.04b 49.89 ± 0.08c 39.26 ± 0.12a
  1. 1Values represented as mean ± SD (n = 6). Values with different superscripts are significant (p < 0.05)
  2. 2LDL low-density lipoprotein cholesterol, HDL high-density lipoprotein cholesterol, SGPT serum glutamate-pyruvate transaminase, SGOT serum glutamic oxaloacetic transaminase, D diabetic, MCC2759 and MCC2760 L. fermentum spp