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Modeling of Sarcomere Contraction Kinetics

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Abstract

Muscle contraction mechanism has been studied on microlevel (chemical reactions in a sarcomere). Sarcomere contraction mechanism is based on interaction between actin and myosin filaments and can be described by a chemical reaction which has a mathematical model in the form of ordinary differential equations system. The most effective for solution of inverse kinetic problem for this system is a parallel variant of genetic algorithm. Parallel computations have been used for effective organization of computational process.

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Authors and Affiliations

  1. Department of Automation and Biomechanics, Technical University of Lodz, Stefanowskiego St. 1/15, 90-924, Lodz, Poland

    Jan Awrejcewicz

  2. Department of Mathematical Modeling, Bashkir State University, Prospect Oktyabrya, 176/1-56, 450055, Ufa, Russia

    Yuliya B. Lind

  3. Department of Mathematical Modeling, Bashkir State University, Kommunarov, 55-11, 450055, Ufa, Russia

    Darya S. Kazakova

Authors
  1. Jan Awrejcewicz
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  2. Yuliya B. Lind
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  3. Darya S. Kazakova
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Correspondence to Yuliya B. Lind.

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Awrejcewicz, J., Lind, Y.B. & Kazakova, D.S. Modeling of Sarcomere Contraction Kinetics. Differ Equ Dyn Syst 21, 15–19 (2013). https://doi.org/10.1007/s12591-012-0115-9

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  • DOI: https://doi.org/10.1007/s12591-012-0115-9

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