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Effects of two aerobic exercise training protocols on parameters of oxidative stress in the blood and liver of obese rats

  • Daniela Delwing-de Lima
  • Ariene Sampaio Souza Farias Ulbricht
  • Carla Werlang-Coelho
  • Débora Delwing-Dal Magro
  • Victor Hugo Antonio Joaquim
  • Eloise Mariani Salamaia
  • Silvana Rodrigues de Quevedo
  • Larissa Desordi
Original Paper

Abstract

We evaluated the effects of moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT) protocols on the alterations in oxidative stress parameters caused by a high-fat diet (HFD), in the blood and liver of rats. The HFD enhanced thiobarbituric acid reactive substances (TBA-RS) and protein carbonyl content, while reducing total sulfhydryl content and catalase (CAT) and glutathione peroxidase (GSH-Px) activities in the blood. Both training protocols prevented an increase in TBA-RS and protein carbonyl content, and prevented a reduction in CAT. HIIT protocol enhanced SOD activity. In the liver, HFD didn’t alter TBA-RS, total sulfhydryl content or SOD, but increased protein carbonyl content and CAT and decreased GSH-Px. The exercise protocols prevented the increase in protein carbonyl content and the MICT protocol prevented an alteration in CAT. In conclusion, HFD elicits oxidative stress in the blood and liver and both protocols prevented most of the alterations in the oxidative stress parameters.

Keywords

Aerobic exercise training protocols Oxidative stress Blood Liver 

Notes

Acknowledgements

This work was supported by grants from Universidade da Região de Joinville.

Compliance with ethical standards

Conflict of interest

The authors declare that there are no conflicts of interest regarding the publication of this paper.

Ethical statement

This study was conducted in accordance with the national and institutional guidelines for the care and use of animals.

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Copyright information

© The Physiological Society of Japan and Springer Japan KK, part of Springer Nature 2017

Authors and Affiliations

  • Daniela Delwing-de Lima
    • 1
    • 2
  • Ariene Sampaio Souza Farias Ulbricht
    • 2
  • Carla Werlang-Coelho
    • 3
    • 4
  • Débora Delwing-Dal Magro
    • 5
  • Victor Hugo Antonio Joaquim
    • 2
    • 3
  • Eloise Mariani Salamaia
    • 1
  • Silvana Rodrigues de Quevedo
    • 6
  • Larissa Desordi
    • 6
  1. 1.Departamento de MedicinaUniversidade da Região de Joinville–UNIVILLEJoinvilleBrasil
  2. 2.Programa de Pós-Graduação em Saúde e Meio AmbienteUniversidade da Região de Joinville–UNIVILLEJoinvilleBrasil
  3. 3.Departamento de Educação FísicaUniversidade da Região de Joinville–UNIVILLEJoinvilleBrasil
  4. 4.Departamento de Química, Universidade do Estado de Santa Catarina (UDESC-Joinville)JoinvilleBrasil
  5. 5.Departamento de Ciências Naturais, Centro de Ciências Exatas e Naturais, Universidade Regional de BlumenauBlumenauBrasil
  6. 6.Departamento de FarmáciaUniversidade da Região de Joinville–UNIVILLEJoinvilleBrasil

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