Skip to main content

Advertisement

Log in

Nimura lecture: “Three EBMs”

  • Review Article
  • Published:
Journal of Echocardiography Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Abstract

The three EBMs in the title refer to the following concepts: evidence-based medicine, experience-based medicine, and echo-based medicine. Evidence-based medicine: I have carried out the following clinical research using transthoracic Doppler echocardiography: (1) noninvasive pulsed-wave Doppler echocardiographic detection of the direction of shunt flow in patients with atrial septal defect: usefulness of the right parasternal approach (1985), (2) significance of laminar systolic regurgitant flow in patients with tricuspid regurgitation: a combined pulsed-wave, continuous-wave, and two-dimensional echocardiography (1990), (3) obstruction of the inferior vena caval orifice by the giant left atrium in patients with mitral stenosis: a Doppler echocardiographic study from the right parasternal approach (1992), and (4) demonstration of a localized acceleration flow signal in the transmural penetrating coronary artery using transthoracic color and pulsed-wave Doppler echocardiography in patients with hypertrophic cardiomyopathy (1996–2017). Experience-based medicine: Dr. Eugene Braunwald says “The best book of cardiology is the patient itself.” I have conducted my modest research activities gleaning hints through day-to-day routine work and sometimes investigating experimentally using the Doppler echocardiographic method. I have also learned from the Japanese Society of Echocardiography that a physician should stand between evidence-based medicine and experience-based medicine. Echo-based medicine: This term is intended to express my personal determination. I believe that echocardiography is the stethoscope of the 21st century. It is a safe, painless, low-cost, and repeatable tool at the bedside. I expect that echocardiography can reduce unnecessary healthcare costs and appropriately select reasonable examinations for patients. I would like to devote the time left in my career to the study of cardiovascular medicine, believing in the power of echocardiography and the Doppler method to provide a link between evidence-based medicine and experience-based medicine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
Fig. 13

Similar content being viewed by others

References

  1. Shub C, Dimopoulos IN, Seward JB, et al. Sensitivity of two-dimensional echocardiography in the direct visualization of atrial septal defect utilizing the subcostal approach: experience with 154 patients. J Am Coll Cardiol. 1983;2:127–35.

    Article  CAS  PubMed  Google Scholar 

  2. Weyman AE, Wann LS, Caldwell RL, et al. Negative contrast echocardiography: a new method for detecting left-to-right shunts. Circulation. 1979;59:498–505.

    Article  CAS  PubMed  Google Scholar 

  3. Tei C, Tanaka H, Kashima T, et al. Real-time cross-sectional echocardiographic evaluation of the interatrial septum by right atrium-interatrial septum- left atrium direction of ultrasound beam. Circulation. 1979;60:539–46.

    Article  CAS  PubMed  Google Scholar 

  4. Tei C, Tanaka H, Nakao S, et al. Motion of the interatrial septum in acute mitral regurgitation. Clinical and experimental echocardiographic studies. Circulation. 1980;62:1080–8.

    Article  CAS  PubMed  Google Scholar 

  5. Levin AR, Spach MS, Boineau JP, et al. Atrial pressure-flow dynamics in atrial septal defects (secundum type). Circulation. 1968;37:476–88.

    Article  CAS  PubMed  Google Scholar 

  6. Alexander JA, Reinbert JC, Sealy WC, et al. Shunt dynamics in experimental atrial septal defects. J Appl Physiol. 1975;39:281–6.

    Article  CAS  PubMed  Google Scholar 

  7. Minagoe S, Tei C, Kisanuki A, et al. Noninvasive pulse Doppler echocardiographic detection of the direction of shunt flow in patients with atrial septal defect: usefulness of the right parasternal approach. Circulation. 1985;71:745–53.

    Article  CAS  PubMed  Google Scholar 

  8. Hatle L, Angelsen B. Doppler ultrasound in cardiology. Philadelphia: Lea & Febige; 1982.

    Google Scholar 

  9. Miyatake K, Okamoto M, Kinoshita N, et al. Evaluation of tricuspid regurgitation by pulsed Doppler echocardiography. Circulation. 1982;66:777–84.

    Article  CAS  PubMed  Google Scholar 

  10. Minagoe S, Chandraratna PAN, Rahimtoola SHB. Significance of laminar systolic regurgitant flow in patients with tricuspid regurgitation: a combine pulse-wave, continuous-wave and two dimensional echocardiography. Am Heart J. 1990;119:627–35.

    Article  CAS  PubMed  Google Scholar 

  11. Kitabatake A, Inoue M, Tanouchi J, et al. Transmitral blood flow reflecting diastolic behavior of the left ventricle in health and disease: a study by pulsed Doppler technique. Jpn Circ J. 1982;46:92–102.

    Article  CAS  PubMed  Google Scholar 

  12. Minagoe S, McKay CR, Chandraratna PAN. Doppler echocardiographic left ventricular filling dynamics in patients with right ventricular overload (abstr). Circulation. 1985;72:III–352 (58th Scientific Sessions held November 11–14, 1985, in Washington D.C.).

    Google Scholar 

  13. Louie EK, Rich S, Brundage BH. Doppler echocardiographic assessment of impaired left ventricular filling in patient with right ventricular pressure overload due to primary pulmonary hypertension. J Am Coll Cardiol. 1986;8:1298–306.

    Article  CAS  PubMed  Google Scholar 

  14. Minagoe S, Yoshikawa J, Yoshida K, et al. Obstruction of the inferior vena caval orifice by the giant left atrium in patients with mitral stenosis: a Doppler echocardiographic study from the right parasternal approach. Circulation. 1992;86:214–25.

    Article  CAS  PubMed  Google Scholar 

  15. Minagoe S, Toyama Y, Yamaguchi H, et al. Transthoracic Doppler echocardiographic detection of intramyocardial coronary artery flow in humans using high frequency transducer. J Cardiol. 1997;30:149–55.

    CAS  PubMed  Google Scholar 

  16. Kim WS, Minagoe S, Mizukami N, et al. No reflow-like pattern in intramyocardial coronary artery suggests myocardial ischemia in patients with hypertrophic cardiomyopathy. J Cardiol. 2008;52:7–16.

    Article  PubMed  Google Scholar 

  17. Canty JM, Dunker DJ. Coronary blood flow and myocardial ischemia. Braunwald’s heart disease: a textbook of cardiovascular medicine. 10th ed. Philadelphia: Saunders; 2015. p. 1039.

    Google Scholar 

  18. Camici PG, Crea F. Coronary microvascular dysfunction. N Engl J Med. 2007;356:830–40.

    Article  CAS  PubMed  Google Scholar 

  19. Crea F, Lanza GA, Camici PG. Comparative summary of the available methods to investigate coronary microvascular function. Coronary microvascular dysfunction. Milan: Springer; 2014.

    Google Scholar 

  20. Maron BJ, Wolfson JK, Epstein SE, et al. Intramural (“small vessels”) coronary artery disease in hypertrophic cardiomyopathy. J Am Coll Cardiol. 1986;8:545–57.

    Article  CAS  PubMed  Google Scholar 

  21. Tanaka M, Fujiwara H, Onodera T, et al. Quantitative analysis of narrowing of intramyocardial small arteries in normal hearts, hypertensive hearts, and hearts with hypertrophic cardiomyopathy. Circulation. 1987;75:1130–9.

    Article  CAS  PubMed  Google Scholar 

  22. Jaski BE. The 4 stages of heart failure. Minnesota: Cardiotext; 2015. p. 42.

    Google Scholar 

  23. Meet the history: Application of the ultrasound Doppler method to cardiac examination. Shinzo 2010;42:1500–12.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shinichi Minagoe.

Ethics declarations

Conflict of interest

Shinichi Minagoe declares that he has no conflicts of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Minagoe, S. Nimura lecture: “Three EBMs”. J Echocardiogr 16, 6–19 (2018). https://doi.org/10.1007/s12574-017-0369-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12574-017-0369-x

Keywords

Navigation