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Spontaneous dissection of the arterial duct during continuous infusion of prostaglandin E1 in a neonate with aortic arch interruption

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Abstract

We report a 3-day-old boy with double outlet of the right ventricle and interruption of the aortic arch who developed spontaneous dissection of the arterial duct (DA) despite use of continuous infusion of lipo-prostaglandin E1 (PGE1). Transthoracic echocardiography demonstrated the spontaneous dissecting aneurysm of DA, which was confirmed by histology at the modified Norwood procedure done at age of 18 days. This is the first report of spontaneous dissection of DA in a neonate receiving PGE1, suggesting a new closing mechanism of DA.

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Conflict of interest

There are no financial or other relations that could lead to a conflict of interest.

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Authors and Affiliations

  1. Department of Pediatric Cardiology, Nagano Children’s Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan

    Nao Inoue, Satoshi Yasukochi, Kiyohiro Takigiku, Hikoro Matsui, Kohta Takei, Yusuke Nakano, Tessyu Otagiri & Yuichiro Hashida

  2. Department of Pathology, Nagano Children’s Hospital, Azumino, Japan

    Yoshifumi Ogiso

  3. Department of Cardiothoracic Surgery, Nagano Children’s Hospital, Azumino, Japan

    Yoshiyuki Maekawa, Kentaro Umezu, Takahiko Sakamoto & Yorikazu Harada

Authors
  1. Nao Inoue
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  2. Satoshi Yasukochi
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  3. Kiyohiro Takigiku
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  4. Hikoro Matsui
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  5. Kohta Takei
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  6. Yusuke Nakano
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  7. Tessyu Otagiri
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  8. Yuichiro Hashida
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  9. Yoshifumi Ogiso
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  10. Yoshiyuki Maekawa
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  11. Kentaro Umezu
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  12. Takahiko Sakamoto
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  13. Yorikazu Harada
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Corresponding author

Correspondence to Satoshi Yasukochi.

Electronic supplementary material

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12574_2013_188_MOESM1_ESM.avi

Supplementary material 1 (AVI 5922 kb). Transthoracic echocardiography. The dissection runs through the media of the ductus arteriosus

Supplementary material 2 (AVI 4839 kb). Color Doppler transthoracic echocardiography

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Inoue, N., Yasukochi, S., Takigiku, K. et al. Spontaneous dissection of the arterial duct during continuous infusion of prostaglandin E1 in a neonate with aortic arch interruption. J Echocardiogr 11, 155–157 (2013). https://doi.org/10.1007/s12574-013-0188-7

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  • DOI: https://doi.org/10.1007/s12574-013-0188-7

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