Abstract
Numerical simulations are performed for two-dimensional steady and pulsatile flow of blood through a channel with single as well as double stenosis (with varying gap) under aortic conditions (Re = 4000). A shear-thinning model based on experimental data is used for blood. The governing equations are developed in terms of vorticity and stream function and solved using a finite difference scheme with full-multigrid algorithm. Peak wall shear stress increases with both length of stenosis, and gap between stenosis; however, the effect of increasing length is much more compared to gap. Pulsatility plays a key role by shifting the location of peak wall shear stress from the primary to the secondary stenosis, and back again, during a cycle. This result is of importance when developing a model for plaque growth based purely on mechanical factors.
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Acknowledgments
We thank Dr. Kirti Chandra Sahu for his valuable suggestions. NN was supported by the MHRD Fellowship for Research Scholars administered by IIT Hyderabad. We thank the Science and Engineering Research Board (SERB), of the Department of Science and Technology, for funding this work under the Fasttrack Scheme for Young Scientists Grant No. SR/FTP/ETA-16/2011.
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Nandakumar, N., Anand, M. Pulsatile flow of blood through a 2D double-stenosed channel: effect of stenosis and pulsatility on wall shear stress. Int J Adv Eng Sci Appl Math 8, 61–69 (2016). https://doi.org/10.1007/s12572-016-0165-2
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DOI: https://doi.org/10.1007/s12572-016-0165-2