Fisheries Science

, Volume 81, Issue 3, pp 533–539 | Cite as

Pseudo-nitzschia fukuyoi (Bacillariophyceae), a domoic acid-producing species from Nha Phu Bay, Khanh Hoa Province, Vietnam

  • Ha Viet Dao
  • Vy Bao Phan
  • Sing Tung Teng
  • Hajime Uchida
  • Chui Pin Leaw
  • Po Teen Lim
  • Toshiyuki Suzuki
  • Ky Xuan Pham
Original Article Chemistry and Biochemistry


Two strains of Pseudo-nitzschia fukuyoi isolated from Vietnamese waters produce domoic acid, a toxin responsible for amnesic shellfish poisoning. Species identification was based on detailed morphological observation using a transmission electron microscope and also molecular data on large subunit (LSU) and the second internal transcribed spacer (ITS2) with NCBI nucleotide Blast (blastn). Toxin productivity of the two strains was confirmed and their range were 3.85–4.54 pg/cell by analyses using LC–MS/MS. This is the first report of occurrence of P. fukuyoi in Vietnamese waters, and the first confirmation of productivity of domoic acid of the species.


Domoic acid Amnesic shellfish toxin Pseudo-nitzschia fukuyoi Vietnam 



This study was funded by project 106.99-2010.22—NAFOSTED, Vietnam. The authors wish to express the deep thank to Dr. Stephen S. Bates (Fisheries and Oceans Canada, Gulf Fisheries Centre, Canada) for the help to improve the manuscript, both in scientific ideas and English correction.


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Copyright information

© Japanese Society of Fisheries Science 2015

Authors and Affiliations

  • Ha Viet Dao
    • 1
  • Vy Bao Phan
    • 1
  • Sing Tung Teng
    • 2
  • Hajime Uchida
    • 3
  • Chui Pin Leaw
    • 4
  • Po Teen Lim
    • 4
  • Toshiyuki Suzuki
    • 3
  • Ky Xuan Pham
    • 1
  1. 1.Institute of OceanographyVietnam Academy of Science and TechnologyNhatrangVietnam
  2. 2.Faculty of Resource Science and TechnologyUniversiti Malaysia SarawakSarawakMalaysia
  3. 3.Tohoku National Fisheries Research InstituteShiogamaJapan
  4. 4.Bachok Marine Research Station, Institute of Ocean and Earth SciencesUniversity of MalayaKelantanMalaysia

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