HIV Infection Control: A Constructive Algorithm for a State-based Switching Control

  • Paolo Di Giamberardino
  • Daniela Iacoviello
Technical Notes and Correspondence


The control of the HIV infection is considered in the framework of the optimal control theory within the problem of resource allocation. A control action, changing the intervention strategy on the basis of the updated situations, is proposed. The switching instants are not fixed in advance but are determined along with the final control time. A constructive algorithm to compute iteratively the switching control is outlined. The solutions obtained provide interesting and promising results.


Epidemic models HIV model piece-wise constant control state-based switching cost function 


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Copyright information

© Institute of Control, Robotics and Systems and The Korean Institute of Electrical Engineers and Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Computer, Control and Management Engineering Antonio RubertiSapienza University of RomeRomeItaly

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