HIV Infection Control: A Constructive Algorithm for a State-based Switching Control
- 1 Downloads
The control of the HIV infection is considered in the framework of the optimal control theory within the problem of resource allocation. A control action, changing the intervention strategy on the basis of the updated situations, is proposed. The switching instants are not fixed in advance but are determined along with the final control time. A constructive algorithm to compute iteratively the switching control is outlined. The solutions obtained provide interesting and promising results.
KeywordsEpidemic models HIV model piece-wise constant control state-based switching cost function
Unable to display preview. Download preview PDF.
- P. Di Giamberardino, L. Compagnucci, C. De Giorgi, and D. Iacoviello, “A new model of the HIV/AIDS infection diffusion and analysis of the intervention effects,” Proc. of 25th IEEE Mediterranean Conference on Control and Automation, pp. 291–296, 2017.Google Scholar
- H. Chang and A. Astolfi, “Control of HIV infection dynamics,” IEEE Control Systems, vol. 28, no. 2, pp. 28–39, 2009.Google Scholar
- E. C. Yuan, D. L. Alderson, S. Stromberg, and J. M. Carlson, “Optimal vaccination in a stochastic epidemic model of two non-interacting populations,” PLOS ONE, pp. 1–25, 2015.Google Scholar
- H. Shim, S. J. Han, C. C. Chung, S.W. Nam, and J. H. Seo, “Optimal scheduling of drug treatment for HIV infection: continuous dose control and receding horizon control,” International Journal of Control, Automation, and Systems, vol. 1, no. 3, pp. 282–288, 2003.Google Scholar