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Early prediction model for coronary heart disease using genetic algorithms, hyper-parameter optimization and machine learning techniques

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Abstract

Coronary Heart Disease (CHD) is one of the major causes of morbidity and mortality worldwide. According to the World Health Organization (WHO) survey, Cardiac arrest accounts for more deaths annually than any other cause. But the silver lining over here is that heart related diseases are highly preventable, if simple lifestyle modifications are carried out. However, it is a challenging factor to identify high risk heart patients at times due to other comorbidity factors such as diabetes, high blood pressure, high cholesterol and so on. Hence it is needed to develop an efficient early prediction model which can detect high risk patients and their life could be saved. The proposed system helps to identify the best set of features for diagnosis using traditional machine learning algorithms along with modern Gradient Boosting approaches. Genetic algorithm for feature selection to optimize performance by reducing the number of parameters by 20% whilst keeping the accuracy of the model intact is implemented in the proposed system. In addition, hyper parameter optimization techniques are executed to further improve the predictive model’s performance.

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References

  1. World health statistics 2020: monitoring health for the SDGs, sustainable development goals. Geneva: World Health Organization; 2020. Licence: CC BY- NC-SA 3.0 IGO.

  2. Kow CS, Zaidi STR, Hasan SS. Cardiovascular Disease and Use of Renin-Angiotensin System Inhibitors in COVID-19. American Journal of Cardiovascular Drugs. 2020. https://doi.org/10.1007/s40256-020-00406-0.

    Article  Google Scholar 

  3. Global Burden of Cardiovascular Disease. Cardiovascular Diseases in India - Current Epidemiology and Future Directions. Centre for Control of Chronic Conditions, Public Health Foundation of India, Gurgaon, India (D.P., P.J.); and All India Institute of Medical Sciences, New Delhi, India (A.R.) https://doi.org/10.1161/CIRCULATIONAHA.114.008729

  4. Chandola T. Ethnic and class differences in health in relation to British South Asians: using the new National Statistics Socio-Economic Classification. Soc Sci Med. 2001;52:1285–96.

    Article  Google Scholar 

  5. Patel K, Hipskind JE. Cardiac Arrest. [Updated 2020 Jan 21]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK534866/.

  6. World Health Organization. Prevention of cardiovascular disease : guidelines for assessment and management of total cardiovascular risk, ISBN 978 92 4 154717 8. 2007.

  7. Chang C-C, Kao J-H, Hsu C-Y, Liaw H-T, Wang T-C. Data Mining Technology Combined with Out-of- Hospital Cardiac Arrest. Symptom Association and Prediction Model Probing. 2018. https://doi.org/10.1007/978-981-10-7398-4_31.

    Article  Google Scholar 

  8. Elmer J, Jones BL, Nagin DS. Comparison of parametric and nonparametric methods for outcome prediction using longitudinal data after cardiac arrest. Resuscitation. 2020;148:152–60. https://doi.org/10.1016/j.resuscitation.2020.01.020.

    Article  Google Scholar 

  9. Uyar H, Yesil E, Karadeniz M, et al. The Effect of High Lactate Level on Mortality in Acute Heart Failure Patients With Reduced Ejection Fraction Without Cardiogenic Shock. Cardiovasc Toxicol. 2020;20:361–9. https://doi.org/10.1007/s12012-020-09563-9.

    Article  Google Scholar 

  10. Layeghian Javan S, Sepehri MM, Layeghian Javan M, Khatibi T. An intelligent warning model for early prediction of cardiac arrest in sepsis patients. Comput Methods Programs Biomed. 2019;178:47–58. https://doi.org/10.1016/j.cmpb.2019.06.010.

    Article  Google Scholar 

  11. Usha M, Debabrata S, Dilip C. IoT-Based Cardiac Arrest Prediction Through Heart Variability Analysis. 2020. https://doi.org/10.1007/978-981-15-1483-8_30.

    Article  Google Scholar 

  12. Luescher T, Mueller J, Isenschmid C, et al. Neuron-specific enolase (NSE) improves clinical risk scores for prediction of neurological outcome and death in cardiac arrest patients: Results from a prospective trial. Resuscitation. 2019;142:50–60. https://doi.org/10.1016/j.resuscitation.2019.07.003.

    Article  Google Scholar 

  13. Piscator E, Göransson K, Forsberg S, et al. Prearrest prediction of favourable neurological survival following in-hospital cardiac arrest: The Prediction of outcome for In-Hospital Cardiac Arrest (PIHCA) score. Resuscitation. 2019;143:92–9. https://doi.org/10.1016/j.resuscitation.2019.08.010.

    Article  Google Scholar 

  14. Seki T, Tamura T, Suzuki M, SOS-KANTO 2012 Study Group. Outcome prediction of out-of-hospital cardiac arrest with presumed cardiac aetiology using an advanced machine learning technique. Resuscitation. 2019;141:128–135. https://doi.org/10.1016/j.resuscitation.2019.06.006

  15. Nachiket T, Tushar L, Damodar R, Venkatanaresh K. Prediction of cardiac arrest recurrence using ensemble classifiers. Sadhana - Academy Proceedings in Engineering Sciences. 2017;42:1–7. https://doi.org/10.1007/s12046-017-0683-z.

    Article  MathSciNet  MATH  Google Scholar 

  16. Akrivos E, Vasilios P, Maglaveras N, Ioanna C. Prediction of Cardiac Arrest in Intensive Care Patients Through Machine Learning. 2018. https://doi.org/10.1007/978-981-10-7419-6_5.

    Article  Google Scholar 

  17. Rubini PE, Deeksha GS, Varshaa Shree B, Deepa N, Srivastava A. A Cardiovascular Disease Prediction using Machine Learning Algorithms. International Journal of Engineering and Advanced Technology (IJEAT) ISSN: 2249–8958, Volume-8 Issue-5, June 2019.

  18. Lingaraj H. A Study on Genetic Algorithm and its Applications. International Journal of Computer Sciences and Engineering. 2016;4:139–43.

    Google Scholar 

  19. Chaikla N, Qi Y. Genetic algorithms in feature selection. IEEE SMC'99 Conference Proceedings. 1999 IEEE International Conference on Systems, Man, and Cybernetics (Cat. No.99CH37028), Tokyo, Japan, 1999, pp. 538–540 vol.5, https://doi.org/10.1109/ICSMC.1999.815609.

  20. Paek A, Agashe H, Contreras-Vidal J. Decoding repetitive finger movements with brain activity acquired via non- invasive electroencephalography. Frontiers in neuroengineering. 2014;7:3. https://doi.org/10.3389/fneng.2014.00003.

    Article  Google Scholar 

  21. Chehouri A, Younes R, Perron J, Ilinca A. A Constraint- Handling Technique for Genetic Algorithms using a Violation Factor. Adam Chehouri et al. / Journal of Computer Sciences. 2016;12(7):350.362. https://doi.org/10.3844/jcssp.2016.350.362.

  22. Genetic Algorithms, tutorialspoint by Tutorials Point (I) Pvt. Ltd (2016) Available from : https://www.tutorialspoint.com/genetic_algorithms.

  23. Bühlmann P. Bagging. Boosting and Ensemble Methods: Handbook of Computational Statistics; 2012. https://doi.org/10.1007/978-3-642-21551-3_33.

    Book  MATH  Google Scholar 

  24. Fu W, Olson R, Nathan, Jena G, PGijsbers, Augspurger T, Carnevale R. (2020, June 1). EpistasisLab/tpot: v0.11.5 (Version v0.11.5). Zenodo. https://doi.org/10.5281/zenodo.3872281.

  25. Olson RS, Bartley N, Urbanowicz RJ, Moore JH. Evaluation of a Tree‐based Pipeline Optimization Tool for Automating Data Science. Proceedings of GECCO 2016. 2015;485‐492.

    Article  Google Scholar 

  26. Shidha MV, Mahalekshmi T. An Empirical Study on the Effect of Resampling Techniques in Imbalanced Datasets for Improving Consistency of Classifiers. International Journal of Applied Engineering Research ISSN 0973–4562 Volume 14, Number 7 (2019) pp. 1516–1525 © Research India Publications. https://www.ripublication.com.

  27. Chawla NV, Bowyer KW, Hall LO, Kegelmeyer WP. SMOTE: Synthetic Minority Over-sampling Technique. Journal of Artificial Intelligence Research, AI Access Foundation, June 2002, ISSN : 1076–9757, volume - 16, pg.nos. 321–357, https://doi.org/10.1613/jair.953.

  28. He H, Ma Y. Imbalanced Learning - Foundations, Algorithms and Applications. Wiley-IEEE Press; 1 edition (July 1, 2013), ISBN: 978–1118074626.

  29. Kjell J, Max K. Applied Predictive Modeling. Springer 5th Edition 2016 ISBN: 978-1461468486 Page 30. https://doi.org/10.1007/978-1-4614-6849-3.

  30. Le TT, Fu W, Moore JH. Scaling tree‐based automated machine learning to biomedical big data with a feature set selector. Bioinformatics. 2020;36(1):250–256.

    Article  Google Scholar 

  31. Mukherjee R, Ghorai SK, Gupta B, et al. Development of a Wearable Remote Cardiac Health Monitoring with Alerting System. Instrum Exp Tech 2020;63:273–283. https://doi.org/10.1134/S002044122002013X.

    Article  Google Scholar 

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Correspondence to Priya R. L.

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L, P.R., Jinny, S.V. & Mate, Y.V. Early prediction model for coronary heart disease using genetic algorithms, hyper-parameter optimization and machine learning techniques. Health Technol. 11, 63–73 (2021). https://doi.org/10.1007/s12553-020-00508-4

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