Skip to main content

Advertisement

Log in

Cervical cancer prognosis using genetic algorithm and adaptive boosting approach

  • Original Paper
  • Published:
Health and Technology Aims and scope Submit manuscript

Abstract

Cervical cancer is fourth main causes of death in women. Cervix is the main origin of cervical cancer. The idea of this research is to explore and propose an efficient and improved prediction method of cervical cancer. Earlier detection and prediction methods/test were very complex, tedious and requires medical and pathological expertise. In this paper, Machine learning approach is used for prediction and detection of cervical cancer. Integrated approach of Genetic Algorithm and Adaptive Boosting is used for performance evaluation for prediction of disease. Genetic algorithm is used as attribute selector to decrease the number of attributes. This not only declines the computational cost but also reduces the number of parameters for diagnosis. Adaptive Boosting is used to improve the performance of classifiers. C 4.5 Decision Tree and Support Vector Machine (SVM) are proposed for prediction of disease. Initially 32 attributes are used for prediction of cervical cancer. The numbers of attributes are reduced with genetic algorithm and further performance enhancement is proposed with adaptive boosting technique. With proposed integrated approach of genetic algorithm and adaptive boosting the improved accuracy lies between 94.17%-94.69%, sensitivity 97.36%-98.90%, specificity 93.37%-94.72% and precision 93%-95.17% for Support Vector Machine Radial Bias Function (SVM RBF), SVM Linear and Decision Tree.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. World Health Organization report on cervical cancer available at www.who.int

  2. Exner M, Kuhn A, Stumpp P. Value of diffusion-weighted MRI in diagnosis of uterine cervical cancer: A prospective study evaluating the benefits of DWI compared to conventional MR sequences in a 3T environment. Acta Radiol. 2016;57(7):869–77.

    Article  Google Scholar 

  3. Mcveigh PZ, Syed AM, Milosevic M, Fyles A, Haider MA. Diffusion-weighted MRI in cervical cancer. Eur Radiol. 2008;18(5):1058–64.

    Article  Google Scholar 

  4. Duraisamy K, Jaganathan KS, Bose JC. Methods of Detecting Cervical Cancer. Adv Biol Res. 2011;5(4):226–32.

    Google Scholar 

  5. Brown AJ, Trimble CL. New Technologies for Cervical Cancer Screening. Best Pract Res Clin Obstet Gynaecol. 2012;26(2):233–42.

    Article  Google Scholar 

  6. Raifu AO, El-Zein M, Sangwa-Lugoma G, Ramanakumar A, Walte SD. Determinants of Cervical Cancer Screening Accuracy for Visual Inspection with Acetic Acid (VIA) and Lugol's Iodine (VILI) Performed by Nurse and Physician. PLoS One. 2017;12(1):e0170631.

    Article  Google Scholar 

  7. Gadducci A, Barsotti C, Cosio S, Domenici L, Riccardo AG. Smoking habit, immune suppression, oral contraceptive use, and hormone replacement therapy use and cervical carcinogenesis: A review of the literature. Gynecol Endocrinol. 2011;27(8):597–604.

    Article  Google Scholar 

  8. Luhn P, Walker J, Schiffman M, Zuna RE. The role of co-factors in the progression from human papillomavirus infection to cervical cancer. Gynecol Oncol. 2013;128(2):265–70.

    Article  Google Scholar 

  9. Cervical Cancer Prevention. Available: https://www.cancer.gov/types/cervical/hp/cervical-prevention-pdq. 2015.

  10. Ronco G, Dillner J, Elfström KM, Tunesi S, Snijders PJ, Arbyn M, et al. Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials. Lancet. 2014;383:524–32.

    Article  Google Scholar 

  11. Galgano MT, Castle PE, Atkins KA, Brix WK, Nassau SR, Stoler MH. Using biomarkers as objective standards in the diagnosis of cervical biopsies. Am J Surg Pathol. 2010;34:1077.

    Article  Google Scholar 

  12. Ramaraju H, Nagaveni Y, Khazi A. Use of Schiller’s test versus Pap smear to increase detection rate of cervical dysplasias. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2017;5:1446–50.

    Google Scholar 

  13. Kusy M, Obrzut B, Kluska J. Application of gene expression programming and neural networks to predict adverse events of radical hysterectomy in cervical cancer patients. Med Biol Eng Comput. 2013;51:1357–65.

    Article  Google Scholar 

  14. Sara Moein. Medical Diagnosis using Neural Networks. IGI Global, 2014. 1-310. Web. 29 Aug. 2019. https://doi.org/10.4018/978-1-4666-6146-2.

  15. Kononenko I. Machine learning for medical diagnosis: history, state of the art and perspective. Artif Intell Med. 2001;23:89–109.

    Article  Google Scholar 

  16. Deo RC. Machine Learning in Medicine. Circulation. 2015;132(20):1920–30.

    Article  Google Scholar 

  17. Fernandes K, Chicco D, Cardoso JS, Fernandes J. Supervised Deep Learning Embeddings for the Prediction of Cervical Cancer Diagnosis. PeerJ Computer Science. 2018;4:e154.

    Article  Google Scholar 

  18. Fernandes K, Cardoso JS, Fernandes J. Transfer Learning With Partial Observability Applied to Cervical Cancer Screening. In: Alexandre L, Salvador Sańchez J, Rodrigues J, editors. Iberian, Conference on Pattern Recognition and Image Analysis. Faro: Springer; 2017. p. 243–50.

    Chapter  Google Scholar 

  19. Wu W, Zhou H. Data-Driven Diagnosis of Cervical Cancer With Support Vector Machine-Based Approaches. IEEE Access. 2017;5:25189–95.

    Article  Google Scholar 

  20. Salmeron JL, Rahimi SA, Navali AM, Sadeghpour A. Medical Diagnosis of Rheumatoid Arthritis Using Data Driven PSO-FCM With Scarce Datasets. Neurocomputing. Apr. 2017;232:104–12.

    Article  Google Scholar 

  21. Jassim G, Obeid A, Nasheet HAA. Knowledge, Attitudes, And Practices Regarding Cervical Cancer And Screening Among Women Visiting Primary Health Care Centres In Bahrain. BMC Public Health. 20187;18, 2018(128). https://doi.org/10.1186/s12889-018-5023-7.

  22. Singh A, Pandey B. A New Intelligent Medical Decision Support System Based on Enhanced Hierarchical Clustering and Random Decision Forest for the Classification of Alcoholic Liver Damage, Primary Hepatoma, Liver Cirrhosis, and Cholelithiasis. Journal of Healthcare Engineering. 2018;2018:1469043.

    Article  Google Scholar 

  23. Hastie T, Tibshirani R, Friedman J. The Elements of Statistical Learning. New York: Springer Science & Business Media; 2009.

    Book  Google Scholar 

  24. Abu-Mostafa YS, Magdon-Ismail M, Lin H-T. Learning from Data. 2012. AMLbook.com.

  25. De Fauw J, et al. Clinically Applicable Deep Learning For Diagnosis and Referral in Retinal Disease. Nat Med. Sep 2018;24(9):1342–50.

    Article  Google Scholar 

  26. Wu M, Yan C, Liu H, Liu Q. Automatic Classification of Ovarian Cancer Types From Cytological Images Using Deep Convolutional Neural Networks. Biosci Rep. 2018;38:BSR20180289. https://doi.org/10.1042/BSR20180289.

    Article  Google Scholar 

  27. Liang X, Zhu L, Huang D-S. Multi-Task Ranking SVM For Image Cosegmentation. Neurocomputing. 2017;247:126–36.

    Article  Google Scholar 

  28. Bolón-Canedo V, Ataer-Cansizoglu E, Erdogmus D, KalpathyCramer J, Fontenla-Romero O, Alonso-Betanzos A, et al. Dealing With Inter-Expert Variability in Retinopathy of Prematurity: A Machine Learning Approach. Comput Methods Prog Biomed. 2015;122(1):1–15.

    Article  Google Scholar 

  29. Bolón-Canedo V, Remeseiro B, Alonso-Betanzos A, Campilho A. Machine Learning for Medical Applications, ESANN 2016 proceedings, European Symposium on Artificial Neural Networks, Computational Intelligence and Machine Learning. Bruges (Belgium), 2016, pp 225-234.

  30. Cortes C, Vapnik V. Support-Vector Network. Mach Learn. 1995;20:273–97.

    MATH  Google Scholar 

  31. Hsu C-W, Lin C-J. A Comparison of Methods for Multi-Class Support Vector Machines. IEEE Trans Neural Netw. 2002;13(2):415–25.

    Article  Google Scholar 

  32. Joachims T (1998) Text categorization with support vector machines: learning with many relevant features. in Proceedings of ECML-98, 10th European Conference on Machine Learning, number 1398, pp. 137–142.

  33. Quinlan JR. C4.5: Programs for Machine Learning, The Morgan Kaufmann series in machine learning, Elsevier, 2014.

  34. He H, Garcia EA. Learning from imbalanced data. IEEE Trans Knowledge Data Eng. 2009;21(9):1263–84.

    Article  Google Scholar 

  35. Daskalaki S, Kopanas I, Avouris N. Evaluation of classifiers for an uneven class distribution problem. Appl Artif Intell. 2006;20(5):381–417.

    Article  Google Scholar 

  36. Blagus R, Lusa L. Class prediction for high-dimensional class-imbalanced data. BMC Bioinformatics. 2010;11:523.

    Article  Google Scholar 

  37. Hulse JV, Khoshgoftaar TM, Napolitano A: Experimental perspectives on learning from imbalanced data. In Proceedings of the 24th international conference on Machine learning. Corvallis: Oregon State University; 2007:935–942.

  38. Chawla NV, Bowyer KW, Hall LO, Philip Kegelmeyer W. SMOTE: Synthetic Minority Over-sampling Technique. J Artif Intell Res. 2002;16:321–57.

    Article  Google Scholar 

  39. Cieslak DA, Chawla NW. Striegel A: Combating Imbalance in Network Intrusion Datasets. In Proc IEEE Int. Conf Granular Comput. Atlanta; 2006:732–737.

  40. Fallahi A, Jafari S. An Expert System for Detection of Breast Cancer Using Data Pre processing and Bayesian Network. Int J AdvSci Technol. 2011;34:65–70.

    Google Scholar 

  41. Liu Y, Chawla NV, Harper MP, Shriberg E, Stolcke A. A Study In Machine Learning From Imbalanced Data For Sentence Boundary Detection In Speech. Comput Speech Lang. 2006;20(4):468–94.

    Article  Google Scholar 

  42. MacIsaac KD, Gordon DB, Nekludova L, Odom DT, Schreiber J, Gifford DK, et al. A Hypothesis-Based Approach For Identifying The Binding Specificity of Regulatory Proteins From Chromatin Immuno precipitation Data. Bioinformatics. 2006;22(4):423–9.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Manoj Sharma.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sharma, M. Cervical cancer prognosis using genetic algorithm and adaptive boosting approach. Health Technol. 9, 877–886 (2019). https://doi.org/10.1007/s12553-019-00375-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12553-019-00375-8

Keywords

Navigation