Abstract
A comparative analysis between two problems—apparently unrelated—which are solved in a period of ~400 years, viz., the accurate prediction of both the planetary orbits and the protein structures, leads to inferred conjectures that go far beyond the existence of a common path in their resolution, i.e., observation → pattern recognition → modeling. The preliminary results from this analysis indicate that complementary science, together with a new perspective on protein folding, may help us discover common features that could contribute to a more in-depth understanding of still-unsolved problems such as protein folding.
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Acknowledgements
The author acknowledges support from the IMASL-CONICET-UNSL and thanks Prof. Marcela Renée Becerra Batán for her invaluable assistance in the analysis of the philosophical and epistemological aspects of this work, as well as the anonymous reviewers for their comments and inquiries that made this work more understandable and engaging.
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This work was funded by the Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación (PICT-02212), Argentina.
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Vila, J.A. Protein structure prediction from the complementary science perspective. Biophys Rev 15, 439–445 (2023). https://doi.org/10.1007/s12551-023-01107-z
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DOI: https://doi.org/10.1007/s12551-023-01107-z