Enniatin B and ochratoxin A in the blood serum of workers from the waste management setting

Viegas, Susana; Osteresch, Bernd; Almeida, Ana; Cramer, Benedikt; Humpf, Hans-Ulrich; Viegas, Carla

doi:10.1007/s12550-017-0302-1

Original Article
Published: 29 November 2017

Enniatin B and ochratoxin A in the blood serum of workers from the waste management setting

Susana Viegas ORCID: orcid.org/0000-0003-1015-8760^1,2,
Bernd Osteresch³,
Ana Almeida¹,
Benedikt Cramer³,
Hans-Ulrich Humpf³ &
Carla Viegas^1,2

Mycotoxin Research volume 34, pages 85–90 (2018)Cite this article

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Abstract

The waste management occupational environment is recognized by the simultaneous presence of several substances and biologic agents. Therefore, workers are exposed simultaneously to multiple contaminants. Occupational exposure to aflatoxin B₁ in one Portuguese waste sorting plant was already reported. However, besides this mycotoxin, data regarding fungal contamination showed that exposure to other mycotoxins could be expected. A study was developed to analyze if exposure to other mycotoxins besides aflatoxin B₁ was occurring in the workers from the waste sorting plant previously assessed and to discuss how these findings need to be considered in the risk assessment process. In addition to aflatoxin B₁ detected previously by ELISA, two additional mycotoxins and one mycotoxin degradation product were detected and quantified by a multi-mycotoxin HPLC-MS/MS approach: Enniatin B and ochratoxin A as well as 2’R-ochratoxin A. Besides the confirmation of co-exposure to several mycotoxins, results probably indicate different exposure routes for the mycotoxins reported.

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GIAS, ESTeSL-Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa, Av. D. João II, lote 4.69.01, Parque das Nações, 1990-096, Lisbon, Portugal
Susana Viegas, Ana Almeida & Carla Viegas
Centro de Investigação em Saúde Pública, Escola Nacional de Saúde Pública, Universidade Nova de Lisboa, Avenida Pacre Cruz, 1600-560, Lisbon, Portugal
Susana Viegas & Carla Viegas
Institute of Food Chemistry, Westfälische Wilhelms-Universität Münster, Corrensstr. 45, 48149, Münster, Germany
Bernd Osteresch, Benedikt Cramer & Hans-Ulrich Humpf

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Susana Viegas
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Bernd Osteresch
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Ana Almeida
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Benedikt Cramer
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Hans-Ulrich Humpf
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Carla Viegas
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Correspondence to Susana Viegas.

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The authors declare no conflict of interest. The founding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. The authors have full control of all primary data and agree to allow the journal to review their data if requested.

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Viegas, S., Osteresch, B., Almeida, A. et al. Enniatin B and ochratoxin A in the blood serum of workers from the waste management setting. Mycotoxin Res 34, 85–90 (2018). https://doi.org/10.1007/s12550-017-0302-1

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Received: 25 July 2017
Revised: 16 November 2017
Accepted: 20 November 2017
Published: 29 November 2017
Issue Date: May 2018
DOI: https://doi.org/10.1007/s12550-017-0302-1

Keywords

Mycotoxins
Occupational exposure
Co-exposure
Risk assessment
Food consumption