Abstract
Purpose
Tuberculosis has a global incidence with an estimated 1.86 billion people being affected. Tuberculous lymphadenitis is a chronic specific granulomatous inflammation with caseation necrosis of the lymph nodes. This case report highlights a rare presentation of tuberculous lymphadenitis as an inflammatory swelling in the preauricular and submandibular regions.
Methods and patient
A 12-year-old female patient presented with two solitary swellings in the right preauricular and right submandibular regions which had been present for 1 week. Both swellings were 2 ´ 2 cm in size with signs of inflammation of the overlying skin. The investigations and treatment have been reviewed in the presented report.
Conclusions
Mycobacterial infection must always be considered as a possible differential diagnosis when treating patients with such swellings refractory to normal antibiotic regimes. Tuberculosis normally presents as a cold abscess but this may not always be the case.
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References
Dye C, Scheele S, Dolin P, Pathania V, Raviglione MC. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. JAMA 1999;282:677–86.
WHO Report. Global Tuberculosis Control. 2002. http://www.who.int/gtb/publications/globrep02/downloadpage.html.
Styblo K. The elimination of tuberculosis in The Netherlands. Bull Int Union Tuberc Lung Dis. 1990;65:49–55.
Finch PJ, Millard FJ, Maxwell JD. Risk of tuberculosis in immigrant Asians: culturally acquired immunodeficiency? Thorax. 1991;46:1–5.
Hooper AA. Tuberculous peripheral lymphadenitis. Br J Surg. 1972;59:353–9.
Powell DA, Hunt WG. Tuberculosis in children: an update. Adv Pediatr. 2006;53:279–322.
Morcillo N, Zumarraga M, Imperiale B, Di Giulio B, Chirico C, Kuriger A, et al. Tuberculosis transmission of predominant genotypes of Mycobacterium tuberculosis in northern suburbs of Buenos Aires city region. Rev Argent Microbiol. 2007;39:145–50.
Caruso G, Passàli FM, Salerni L, Molinaro G, Messina M. Head and neck mycobacterial infections in pediatric patients. Int J Pediatr Otorhinolaryngol. 2009;73 Suppl 1:S38–41.
Albright JT, Pransky SM. Nontuberculous mycobacterial infections of the head and neck. Pediatr Clin N Am. 2003;50:503–14.
Carrol ED, Clark JE, Cant AJ. Non-pulmonary tuberculosis. Paediatr Respir Rev. 2001;2:113–9.
Polesky A, Grove W, Bhatia G. Peripheral tuberculous lymphadenitis: epidemiology, diagnosis, treatment, and outcome. Medicine (Baltimore). 2005;84:350–62.
Wang WC, Chen JY, Chen YK, Lin LM. Tuberculosis of the head and neck: a review of 20 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107:381–6.
Dandapat MC, Mishra BM, Dash SP, Kar PK. Peripheral lymph node tuberculosis: a review of 80 cases. Br J Surg. 1990;77:911–2.
Sharma SK, Mohan A. Extrapulmonary tuberculosis. Indian J Med Res. 2004;120:316–53.
Lai KK, Stottmeier KD, Sherman IH, McCabe WR. Mycobacterial cervical lymphadenopathy: relation of etiologic agents to age. JAMA 1984;251:1286–8.
Al-Serhani AM. Mycobacterial infection of the head and neck: presentation and diagnosis. Laryngoscope. 2001;111:2012–6.
Agarwal AK, Sethi A, Sethi D, Malhotra V, Singal S. Tubercular cervical adenitis: clinicopathologic analysis of 180 cases. J Otolaryngol Head Neck Surg. 2009;38:521–5.
Prasad KC, Sreedharan S, Chakravarthy Y, Prasad SC. Tuberculosis in the head and neck: experience in India. J Laryngol Otol. 2007;121:979–85.
Mirza S, Restrepo BI, McCormick JB, Fisher-Hoch SP. Diagnosis of tuberculosis lymphadenitis using a polymerase chain reaction on peripheral blood mononuclear cells. Am J Trop Med Hyg. 2003;69:461–5.
Purohit MR. Gender differences in the clinical diagnosis of tuberculous lymphadenitis—a hospital-based study from Central India. Int J Infect Dis. 2009;13:600–5.
Rinaggio J. Tuberculosis. Dent Clin North Am. 2003;47:449–65.
Balasubramanian R, Ramachandran R. Management of non-pulmonary forms of tuberculosis: review of TRC studies over two decades. Indian J Pediatr. 2000;67:34–40.
Castro DJ, Hoover L, Castro DJ, Zuckerbraun L. Cervical mycobacterial lymphadenitis. Medical vs surgical management. Arch Otolaryngol. 1985;111:816–9.
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Neelakandan, R., Bhargava, D., Kumaran, M. et al. Tuberculous lymphadenitis presenting as inflammatory cervicofacial swelling in a 12-year-old girl. J. Stomat. Occ. Med. 4, 72–75 (2011). https://doi.org/10.1007/s12548-011-0011-x
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DOI: https://doi.org/10.1007/s12548-011-0011-x