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Prot-Prop: J-tool to predict the subcellular location of proteins based on physiochemical characterization

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Abstract

PROT-PROP is a computational tool to characterize 27 physicochemical properties of a protein along with its subcellular location (intra or extra) in a single-window application. Other significant features of this software include calculation of numerical values for hydrophobicity, hydrophilicity; composition of small and large amino acids; net hydrophobic content in terms of low/high; and Navie’s algorithm to calculate theoretical pI. PROT-PROP is an easy-to-install platform independent implementation of JAVA under a user-friendly interface. It is a standalone version as a virtual appliance and source code for platforms supporting Java 1.5.0 and higher versions, and downloadable from the web http://www.mzu.edu.in/schools/biotechnology.html. PROT-PROP can run under Windows and Macintosh Operating Systems. PROT-PROP is distributed with its source code so that it may be adapted or customized, if desired.

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Authors and Affiliations

  1. Bioinformatics Infrastructure Facility, Department of Biotechnology, Mizoram University, Aizawl, 796004, Mizoram, India

    Brindha Senthilkumar, Sangzuala Sailo & Senthilkumar Nachimuthu

  2. Department of Zoology, Mizoram University, Aizawl, 796004, Mizoram, India

    Gurusubramanian Guruswami

Authors
  1. Brindha Senthilkumar
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  2. Sangzuala Sailo
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  3. Gurusubramanian Guruswami
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  4. Senthilkumar Nachimuthu
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Correspondence to Senthilkumar Nachimuthu.

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Senthilkumar, B., Sailo, S., Guruswami, G. et al. Prot-Prop: J-tool to predict the subcellular location of proteins based on physiochemical characterization. Interdiscip Sci Comput Life Sci 4, 296–301 (2012). https://doi.org/10.1007/s12539-012-0143-8

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  • DOI: https://doi.org/10.1007/s12539-012-0143-8

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