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Pathologic etiology and predictors of malignancy in children with cervical lymphadenopathy

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Fig. 1
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Data availability

All data generated during and/or analyzed during this study are available from the corresponding author on reasonable request.

References

  1. Sahai S. Lymphadenopathy. Pediatr Rev. 2013;34:216–27.

    Article  PubMed  Google Scholar 

  2. Leung AK, Davies HD. Cervical lymphadenitis: etiology, diagnosis, and management. Curr Infect Dis Rep. 2009;11:183–9.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Larsson LO, Bentzon MW, Berg Kelly K, Mellander L, Skoogh BE, Strannegård IL, et al. Palpable lymph nodes of the neck in Swedish schoolchildren. Acta Paediatr. 1994;83:1091–4.

    Article  CAS  PubMed  Google Scholar 

  4. Weinstock MS, Patel NA, Smith LP. Pediatric Cervical Lymphadenopathy. Pediatr Rev. 2018;39:433–43.

    Article  PubMed  Google Scholar 

  5. Chang SSY, Xiong M, How CH, Lee DM. An approach to cervical lymphadenopathy in children. Singapore Med J. 2020;61:569–77.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Adesuwa Olu-Eddo N, Egbagbe EE. Peripheral lymphadenopathy in Nigerian children. Niger J Clin Pract. 2006;9:134–8.

    CAS  PubMed  Google Scholar 

  7. Ejeckam GC, Nwabueze ED. Pathology of superficial lymph node in children and young adults in Enugu. Nigeria J Trop Pediatr. 1984;30:307–9.

    Article  CAS  PubMed  Google Scholar 

  8. Aftab M, Hasan M, Samad L. Lymph node biopsy in children: Indications and etiology. J Pediatr Adolesc Sur. 2020;1:28–31.

    Google Scholar 

  9. De Corti F, Cecchetto G, Vendraminelli R, Mognato G. Fine-needle aspiration cytology in children with superficial lymphadenopathy. Pediatr Med Chir. 2014;36:80–2.

    Article  PubMed  Google Scholar 

  10. Reddy MP, Moorchung N, Chaudhary A. Clinico-pathological profile of pediatric lymphadenopathy. Indian J Pediatr. 2002;69:1047–51.

    Article  PubMed  Google Scholar 

  11. Celenk F, Gulsen S, Baysal E, Aytac I, Kul S, Kanlikama M. Predictive factors for malignancy in patients with persistent cervical lymphadenopathy. Eur Arch Otorhinolaryngol. 2016;273:251–6.

    Article  PubMed  Google Scholar 

  12. Tsai JG, Chiang SC, Lin CZ, Chang P. Predicting the probability of malignancy of the neck mass with logistic regression model: a statistical analysis of excisional biopsy of neck masses. Zhonghua Yi Xue Za Zhi (Taipei). 1992;49:328–34.

    CAS  PubMed  Google Scholar 

  13. Nolder AR. Pediatric cervical lymphadenopathy: when to biopsy? Curr Opin Otolaryngol Head Neck Surg. 2013;21:567–70.

    PubMed  Google Scholar 

  14. Şen HS, Ocak S, Yılmazbaş P. Children with cervical lymphadenopathy: reactive or not? Turk J Pediatr. 2021;63:363–71.

    Article  PubMed  Google Scholar 

  15. Oguz A, Karadeniz C, Temel EA, Citak EC, Okur FV. Evaluation of peripheral lymphadenopathy in children. Pediatr Hematol Oncol. 2006;23:549–61.

    Article  PubMed  Google Scholar 

  16. Mönig H, Marquardt D, Arendt T, Kloehn S. Limited value of elevated erythrocyte sedimentation rate as an indicator of malignancy. Fam Pract. 2002;19:436–8.

    Article  PubMed  Google Scholar 

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Acknowledgements

We thank all the patients and their parents for their kind cooperation. We thank all the medical staff who provided care for patients.

Funding

No funding was received for this study.

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Authors and Affiliations

Authors

Contributions

JWK contributed to obtaining institutional approval, acquisition and analysis of data, and drafting and revising the manuscript. JMK assisted in data analysis and drafted and revised the manuscript. JYB, JYL, SML, WKA, SMH, JWH, and CJL carried out the analysis and interpretation of the data, and reviewed and revised the manuscript. JGA conceptualized and designed the study, coordinated and supervised data collection, and drafted and revised the manuscript. All authors read and approved the manuscript.

Corresponding author

Correspondence to Jong Gyun Ahn.

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Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.

Ethical approval

This study was approved by the Institutional Review Board of Severance Hospital (IRB number: 2022–0803-011), and the requirement of obtaining informed consent was waived because of the retrospective nature of the study. The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments.

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Kim, J.W., Baek, J.Y., Lee, J.Y. et al. Pathologic etiology and predictors of malignancy in children with cervical lymphadenopathy. World J Pediatr 19, 283–287 (2023). https://doi.org/10.1007/s12519-022-00667-6

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  • DOI: https://doi.org/10.1007/s12519-022-00667-6

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