Complementary and alternative medicine in ADHD treatment: more soundly designed clinical trials needed

  • Rong-Wang YangEmail author
  • Rong Li
Letter to Editor

We read with great interest the article [1] by Dehbokri et al. published in the Journal recently. The authors carried out a double-blind, randomized clinical trials to study the effects of vitamin D supplementation on children with attention deficit hyperactivity disorder (ADHD) for 6 weeks. The results showed that vitamin D could improve ADHD symptoms with a particular effect on inattention symptoms. It is a significant report to examine whether vitamin D supplementation can benefit ADHD symptoms, which draw our attentions on the interesting topic of vitamin and mineral supplementation in the treatment of ADHD.

ADHD is a neuro-developmental disorder defined by DSM-5 [2], which means the functional impairments of ADHD symptoms to individuals would not limited in childhood [3]. Currently, the treatment strategies recommended by most guidelines include psychopharmacological drugs and behavioral modifications that have been proven effective [4, 5, 6]. Behavioral modifications can...



We thank Prof. Zhao, Dr. Gao, Dr. Zhang and Dr. Lin for their assistance in this work.

Author contributions

RY and RL reviewed the literatures, and wrote the draft. Both the authors approved the final version.



Compliance with ethical standards

Ethical approval

Not needed.

Conflict of interest

No financial or nonfinancial benefits have been received or will be received from any party related directly or indirectly to the subject of this article.


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Copyright information

© Children's Hospital, Zhejiang University School of Medicine 2019

Authors and Affiliations

  1. 1.Department of Child Psychology, Children’s HospitalZhejiang University School of MedicineHangzhouChina

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