World Journal of Pediatrics

, Volume 13, Issue 3, pp 217–221 | Cite as

Impact of relocation and environmental cleaning on reducing the incidence of healthcare-associated infection in NICU

  • Qiu-Fang Li
  • Hong Xu
  • Xiao-Ping Ni
  • Rong Lin
  • Hui Jin
  • Ling-Ya Wei
  • Dan Liu
  • Lin-Hai Shen
  • Jie Zha
  • Xin-Fen Xu
  • Bo Wu
Brief Report



Hospital environment remains a risk for healthcare-associated infections (HAIs). This was a prospective study to evaluate the comprehensive impact of relocating a neonatal intensive care unit (NICU) to a new facility and improved environmental cleaning practice on the presence of methicillin-resistant Staphylococcus aureus (MRSA) on inanimate surfaces and the incident rate of HAIs.


New environmental cleaning measures were adopted after the NICU was moved to a new and better-designed location. The effect of moving and the new environmental cleaning practice was investigated by comparing the positive number of MRSA on ward surfaces and the incidence density of HAIs between the baseline and intervention periods.


Only 2.5% of environmental surfaces were positive for MRSA in the intervention period compared to 44.0% in the baseline period (P<0.001). Likewise, the total incident rate of HAIs declined from 16.8 per 1000 cot-days to 10.0 per 1000 cot-days (P<0.001).


The comprehensive measures of relocating the NICU to a new facility design with improved environmental cleaning practice are effective and significantly reduce the incidence of HAIs.


environmental cleaning intervention healthcare-associated infections methicillin-resistant Staphylococcus aureus 


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Copyright information

© Children's Hospital, Zhejiang University School of Medicine and Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Qiu-Fang Li
    • 1
  • Hong Xu
    • 3
  • Xiao-Ping Ni
    • 3
  • Rong Lin
    • 2
  • Hui Jin
    • 3
  • Ling-Ya Wei
    • 3
  • Dan Liu
    • 1
  • Lin-Hai Shen
    • 3
  • Jie Zha
    • 3
  • Xin-Fen Xu
    • 2
  • Bo Wu
    • 2
  1. 1.Department of NICU, Women’s HospitalZhejiang University School of MedicineHangzhouChina
  2. 2.Department of Infection Control, Women’s HospitalZhejiang University School of MedicineHangzhouChina
  3. 3.Department of Disinfection Surveillance and Vector ControlHangzhou Center for Disease Control and PreventionHangzhouChina

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