World Journal of Pediatrics

, Volume 13, Issue 1, pp 8–14 | Cite as

Sleep disordered breathing in children with achondroplasia

  • Marco Zaffanello
  • Gaetano Cantalupo
  • Giorgio Piacentini
  • Emma Gasperi
  • Luana Nosetti
  • Paolo Cavarzere
  • Diego Alberto Ramaroli
  • Aliza Mittal
  • Franco Antoniazzi
Review article

Abstract

Background

Children with achondroplasia often have breathing problems, especially during sleep. The most important treatments are adenotonsillectomy (for treating upper obstruction) and/or neurosurgery (for resolving cervicomedullar junction stenosis).

Data sources

We reviewed the scientific literature on polysomnographic investigations which assessed the severity of respiratory disorders during sleep.

Results

Recent findings have highlighted the importance of clinical investigations in patients with achondroplasia, differentiating between those that look for neurological patterns and those that look for respiratory problems during sleep. In particular, magnetic resonance imaging (MRI) and somatosensory evoked potentials are the main tools to evaluate necessary neurosurgery and over myelopathy, respectively.

Conclusions

The use of polysomnography enables clinicians to identify children with upper airway obstruction and to quantify disease severity; it is not suitable for MRI and/or neurosurgery considerations.

Key words

achondroplasia children polysomnography sleep disordered breathing upper respiratory tract obstruction 

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Supplementary material

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Sleep disordered breathing in achondroplasia

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Copyright information

© Children's Hospital, Zhejiang University School of Medicine and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Marco Zaffanello
    • 1
    • 4
  • Gaetano Cantalupo
    • 1
  • Giorgio Piacentini
    • 1
  • Emma Gasperi
    • 1
  • Luana Nosetti
    • 2
  • Paolo Cavarzere
    • 1
  • Diego Alberto Ramaroli
    • 1
  • Aliza Mittal
    • 3
  • Franco Antoniazzi
    • 1
  1. 1.Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric DivisionUniversity of VeronaVeronaItaly
  2. 2.Department of PediatricsUniversity of InsubriaVareseItaly
  3. 3.NDMC Medical College and Hindurao HospitalNew DelhiIndia
  4. 4.Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics Pediatric DivisionUniversity of VeronaVeronaItaly

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