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Evaluation of carotid intima-media thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy

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Abstract

Background

Adenotonsillar hypertrophy can produce cardiopulmonary disease in children. However, it is unclear whether adenotonsillar hypertrophy causes atherosclerosis. This study evaluated carotid intimamedia thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy.

Methods

The study included 40 children with adenotonsillar hypertrophy (age: 5-10 years) and 36 healthy children with similar age and body mass index. Systolic blood pressure, diastolic blood pressure, and pulse pressure were measured in all subjects. Carotid intima-media thickness, carotid arterial systolic diameter, and carotid arterial diastolic diameter were measured using a high-resolution ultrasound device. Based on these measurements, carotid arterial strain, carotid artery distensibility, beta stiffness index, and elasticity modulus were calculated.

Results

Carotid intima-media thickness was greater in children with adenotonsillar hypertrophy (0.36±0.05 mm vs. 0.34±0.04 mm, P=0.02) compared to healthy controls. Beta stiffness index (3.01±1.22 vs. 2.98±0.98, P=0.85), elasticity modulus (231.39±99.23 vs. 226.46±83.20, P=0.88), carotid arterial strain (0.17±0.06 vs. 0.17±0.04, P=0.95), and carotid artery distensibility (13.14±3.88 vs. 12.92±3.84, P=0.75) were similar between children with adenotonsillar hypertrophy and the healthy controls.

Conclusions

The present study revealed increased carotid intima-media thickness in children with adenotonsillar hypertrophy. The risk of subclinical atherosclerosis may be higher in children with adenotonsillar hypertrophy.

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Authors and Affiliations

  1. Department of Pediatric Cardiology, Erzurum Region Training and Research Hospital, Erzurum, 25080, Turkey

    Murat Çiftel & Osman Yılmaz

  2. Department of Radiology, Erzurum Training and Research Hospital, Erzurum, Turkey

    Berrin Demir

  3. Department of Ear, Nose, and Throat, Erzurum Training and Research Hospital, Erzurum, Turkey

    Günay Kozan

  4. Neonatal unit, Erzurum Training and Research Hospital, Erzurum, Turkey

    Hasan Kahveci

  5. Department of Pediatric Infectious Diseases, Erzurum Training and Research Hospital, Erzurum, Turkey

    Ömer Kılıç

Authors
  1. Murat Çiftel
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  2. Berrin Demir
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  3. Günay Kozan
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  4. Osman Yılmaz
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  5. Hasan Kahveci
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  6. Ömer Kılıç
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Correspondence to Murat Çiftel.

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Çiftel, M., Demir, B., Kozan, G. et al. Evaluation of carotid intima-media thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy. World J Pediatr 12, 103–108 (2016). https://doi.org/10.1007/s12519-015-0066-7

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  • DOI: https://doi.org/10.1007/s12519-015-0066-7

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